SCHEMBL6749148

SCHEMBL6749148

CC(C)(C)N[Si](C)(C)C1C=C(N2CCCC2)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
TSHR P16473 3/20 0.33
APAF1 O14727 1/20 0.32
TDP2 O95551 1/20 0.32
NSD2 O96028 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
POLB P06746 2/20 0.32
KDM4E B2RXH2 3/20 0.32
MAPT P10636 2/20 0.32
USP2 O75604 2/20 0.32
ALDH1A1 P00352 4/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5679143 0.99 DRD2 (0.33) DRD2DRD4TSHRAPAF1TDP2
SCHEMBL6907620 0.99 TSHR (0.35) DRD2DRD4TSHRAPAF1TDP2
Hydrochloric Acid SCHEMBL6851818 0.97 CYP1A2 (0.32) DRD2DRD4TSHRAPAF1TDP2
Hydrochloric Acid SCHEMBL6865425 0.97 DRD2 (0.32) DRD2DRD4TSHRAPAF1TDP2
Hydrochloric Acid SCHEMBL6851816 0.97 DRD2 (0.32) DRD2DRD4TSHRAPAF1TDP2
Hydrochloric Acid SCHEMBL6865428 0.97 CYP1A2 (0.32) DRD2DRD4TSHRAPAF1TDP2
Hydrochloric Acid SCHEMBL6851446 0.96 TSHR (0.33) DRD2DRD4TSHRAPAF1TDP2
Hydrochloric Acid SCHEMBL6851450 0.96 TSHR (0.33) DRD2DRD4TSHRAPAF1TDP2
Hydrochloric Acid SCHEMBL6864763 0.96 TSHR (0.33) DRD2DRD4TSHRAPAF1TDP2
Hydrochloric Acid SCHEMBL6864767 0.96 TSHR (0.33) DRD2DRD4TSHRAPAF1TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107709383-B Process for the manufacture of polyolefins 陶氏环球技术有限责任公司 2021-03-30 CN disclosed
US-10465020-B2 Process for producing a polyolefin DOW GLOBAL TECHNOLOGIES LLC (US) 2019-11-05 US disclosed
US-20180171041-A1 A PROCESS FOR PRODUCING A POLYOLEFIN DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-21 US disclosed
EP-3303425-A1 A PROCESS FOR PRODUCING A POLYOLEFIN Dow Global Technologies LLC (US) 2018-04-11 EP disclosed
WO-2016196293-A1 A PROCESS FOR PRODUCING A POLYOLEFIN DOW GLOBAL TECHNOLOGIES LLC (US) 2016-12-08 WO disclosed
EP-0923589-B1 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2004-09-15 EP disclosed
WO-2004044018-A2 PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED DIENES AND IN SITU FORMATION OF POLYMER BLENDS AND PRODUCTS MADE THEREBY DOW GLOBAL TECHNOLOGIES, INC. (US) 2004-05-27 WO disclosed
US-6268444-B1 TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION DOW CHEMICAL COMPANY 2001-07-31 US disclosed