Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | APAF1 | O14727 | 4/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749148 | 0.99 | DRD2 (0.33) | TSHRAPAF1NSD2TDP2HKDC1 | |
| Hydrochloric Acid SCHEMBL6864763 | 0.97 | TSHR (0.33) | TSHRAPAF1NSD2TDP2HKDC1 | |
| Hydrochloric Acid SCHEMBL6851446 | 0.97 | TSHR (0.33) | TSHRAPAF1NSD2TDP2HKDC1 | |
| Hydrochloric Acid SCHEMBL6851450 | 0.97 | TSHR (0.33) | TSHRAPAF1NSD2TDP2HKDC1 | |
| Hydrochloric Acid SCHEMBL6864767 | 0.97 | TSHR (0.33) | TSHRAPAF1NSD2TDP2HKDC1 | |
| SCHEMBL5679143 | 0.97 | DRD2 (0.33) | TSHRAPAF1NSD2TDP2HKDC1 | |
| Hydrochloric Acid SCHEMBL6865428 | 0.96 | CYP1A2 (0.32) | TSHRAPAF1NSD2TDP2HKDC1 | |
| Hydrochloric Acid SCHEMBL6851818 | 0.96 | CYP1A2 (0.32) | TSHRAPAF1NSD2TDP2HKDC1 | |
| Hydrochloric Acid SCHEMBL6851816 | 0.96 | DRD2 (0.32) | TSHRAPAF1NSD2TDP2HKDC1 | |
| Hydrochloric Acid SCHEMBL6865425 | 0.96 | DRD2 (0.32) | TSHRAPAF1NSD2TDP2HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |
| EP-0923589-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006727-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |