Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150727 | 0.96 | ALDH1A1 (0.52) | HTR2ACA2ALDH1A1ESR1ADRA2A | |
| SCHEMBL672280 | 0.96 | ALDH1A1 (0.52) | HTR2ACA2ALDH1A1ESR1ADRA2A | |
| SCHEMBL640895 | 0.96 | ALDH1A1 (0.52) | HTR2ACA2ALDH1A1ESR1ADRA2A | |
| SCHEMBL2700648 | 0.80 | ALDH1A1 (0.58) | HTR2AALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL11523008 | 0.80 | ALDH1A1 (0.58) | HTR2AALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL12805346 | 0.79 | ALDH1A1 (0.56) | HTR2AALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL12804559 | 0.79 | ALDH1A1 (0.56) | HTR2AALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL866243 | 0.79 | ALDH1A1 (0.56) | HTR2AALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL2702987 | 0.79 | ALDH1A1 (0.56) | HTR2AALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL672943 | 0.78 | HTR2A (0.51) | HTR2ACA2ALDH1A1ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120252979-A1 | Process for Producing Blends of Syndiotactic, 1,2-Polybutadiene and Rubbery Elastomers | RADEMACHER CHRISTINE (US) | 2012-10-04 | — | — | US | disclosed |
| US-8067503-B2 | Process for producing blends of syndiotactic, 1,2-polybutadiene and rubbery elastomers | BRIDGESTONE CORPORATION (JP) | 2011-11-29 | — | — | US | disclosed |