SCHEMBL640895

SCHEMBL640895

CCCCCCCCCc1ccc([PH](=O)[O-])cc1.CCCCCCCCCc1ccc([PH](=O)[O-])cc1.[Ni+2]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
ESR1 P03372 2/20 0.52
ADRA2A P08913 2/20 0.52
ADORA3 P0DMS8 2/20 0.52
TACR2 P21452 2/20 0.52
SLC6A2 P23975 2/20 0.52
SLC6A4 P31645 2/20 0.52
SLC6A3 Q01959 2/20 0.52
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
SHBG P04278 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
HSPD1 P10809 1/20 0.52
ADRB3 P13945 1/20 0.52
HTR2C P28335 1/20 0.52
HSPE1 P61604 1/20 0.52
HIF1A Q16665 1/20 0.52
TST Q16762 1/20 0.52
HSD17B10 Q99714 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674918 0.96 HTR2A (0.56) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL150727 0.96 ALDH1A1 (0.52) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL672280 0.96 ALDH1A1 (0.52) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL2700648 0.80 ALDH1A1 (0.58) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL11523008 0.80 ALDH1A1 (0.58) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL12805346 0.79 ALDH1A1 (0.56) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL866243 0.79 ALDH1A1 (0.56) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL12804559 0.79 ALDH1A1 (0.56) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL2702987 0.79 ALDH1A1 (0.56) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL30229465 0.78 THRB (0.49) ALDH1A1ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3969490-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND TIRE COMPONENTS BRIDGESTONE CORP (JP) 2026-03-25 EP disclosed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-12264232-B2 Modified high-cis polybutadiene polymer, related methods and tire components BRIDGESTONE CORPORATION (JP) 2025-04-01 US disclosed
US-20250066516-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-02-27 US disclosed
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP disclosed
EP-4457250-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME Bridgestone Corporation (JP) 2024-11-06 EP disclosed
EP-3966259-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2024-10-30 EP disclosed
WO-2023129959-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2023-07-06 WO disclosed
US-20230144912-A1 METAL-BASED CATALYST FOR PRODUCING POLYDIENES BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2023-05-11 US disclosed
EP-4126983-A1 METAL-BASED CATALYST FOR PRODUCING POLYDIENES Bridgestone Americas Tire Operations, LLC (US) 2023-02-08 EP disclosed
US-20220213300-A1 Modified High-Cis Polybutadiene Polymer, Related Methods And Tire Components BRIDGESTONE CORPORATION (JP) 2022-07-07 US disclosed
US-20220144974-A1 Modified High-Cis Polybutadiene Polymer, Related Methods And Rubber Compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2022-05-12 US disclosed
US-8933181-B2 Branched polymers and methods for their synthesis and use BRIDGESTONE CORPORATION (JP) 2015-01-13 US disclosed
US-20130137838-A1 NICKEL-BASED CATALYST COMPOSITION BRIDGESTONE CORPORATION (JP) 2013-05-30 US disclosed
US-20120108755-A1 BRANCHED POLYMERS AND METHODS FOR THEIR SYNTHESIS AND USE BRIDGESTONE CORPORATION (JP) 2012-05-03 US disclosed
US-8119736-B2 Branched polymers and methods for their synthesis and use BRIDGESTONE CORPORATION (JP) 2012-02-21 US disclosed
WO-2011047021-A1 PROCESSES FOR PREPARATION OF CYCLIC ACYCLIC DIENE COPOLYMER AND RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB ALDH1A1 778/4885ESR1 1475/4885ADRA2A 3694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.