Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIK1 | P57059 | 1/20 | 0.52 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.52 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 3/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.41 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752619 | 0.90 | HPGD (0.52) | SIK1SIK2SIK3HPGDMAPT | |
| SCHEMBL2650302 | 0.89 | HPGD (0.50) | SIK1SIK2SIK3HPGDMAPT | |
| SCHEMBL2655791 | 0.87 | ALDH1A1 (0.48) | HPGDMAPTALDH1A1RAB9AFGFR1 | |
| SCHEMBL2652435 | 0.85 | HPGD (0.42) | SIK1SIK2SIK3HPGDMAPT | |
| SCHEMBL2652431 | 0.85 | RIPK1 (0.42) | SIK1SIK2SIK3HPGDMAPT | |
| SCHEMBL6752611 | 0.83 | FGFR1 (0.67) | SIK1SIK2SIK3HPGDALDH1A1 | |
| SCHEMBL6582964 | 0.81 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL31263991 | 0.81 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL6752607 | 0.80 | HPGD (0.51) | SIK1SIK2SIK3HPGDMAPT | |
| SCHEMBL2649765 | 0.80 | HPGD (0.51) | HPGDALDH1A1RAB9ARIPK1RIPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710044-B2 | Technical field | NEUROSEARCH A/S (DK) | 2004-03-23 | — | — | US | claimed |