Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.40 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.40 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13014787 | 1.00 | CPN1 (0.46) | CPN1CPB2GABRR1CYP1A2GABRA5 | |
| Hydrochloric Acid SCHEMBL27500621 | 0.98 | CPN1 (0.45) | CPN1CPB2GABRR1CYP1A2GABRA5 | |
| SCHEMBL1858607 | 0.89 | GABRR1 (0.50) | CPN1CPB2GABRR1CYP1A2GABRA5 | |
| SCHEMBL8507678 | 0.89 | CPN1 (0.44) | CPN1CPB2GABRR1CYP1A2ITGB3 | |
| SCHEMBL4793949 | 0.84 | CPN1 (0.38) | CPN1CPB2GABRR1GABRA5GABRB2 | |
| SCHEMBL6987701 | 0.81 | METAP1 (0.46) | GABRR1CYP1A2 | |
| SCHEMBL61275 | 0.81 | METAP1 (0.46) | GABRR1CYP1A2 | |
| SCHEMBL17590498 | 0.81 | METAP1 (0.46) | GABRR1CYP1A2 | |
| SCHEMBL13406394 | 0.81 | CPN1 (0.58) | CPN1CPB2GABRR1CYP1A2GABRA5 | |
| SCHEMBL21334736 | 0.81 | CPN1 (0.58) | CPN1CPB2GABRR1CYP1A2GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102439007-A | Amide derivatives | DAIICHI SANKYO CO LTD | 2012-05-02 | — | — | CN | disclosed |
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
| CN-1131665-A | Piperazine derivatives, medicaments comprising these compounds, their use and processes for their preparation | THOMAE GMBH DR K (DE) | 1996-09-25 | — | — | CN | disclosed |
| US-5492919-A | IRRITABLE BOWEL DISORDER | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-02-20 | — | — | US | disclosed |
| EP-0596933-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-05-18 | — | — | EP | disclosed |
| WO-1993002677-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | CPN1 4288/4885CPB2 2083/4885GABRR1 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.