Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 14/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 14/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141889 | 0.87 | ICAM1 (0.38) | ICAM1HDAC6 | |
| SCHEMBL6747260 | 0.84 | ICAM1 (0.35) | ICAM1HDAC6 | |
| SCHEMBL6745730 | 0.73 | HDAC6 (0.43) | ICAM1HDAC6 | |
| SCHEMBL6745329 | 0.73 | ICAM1 (0.37) | ICAM1HDAC6 | |
| SCHEMBL6747454 | 0.72 | HDAC6 (0.43) | ICAM1HDAC6 | |
| SCHEMBL6749064 | 0.71 | HDAC6 (0.41) | ICAM1HDAC6 | |
| SCHEMBL6745847 | 0.71 | HDAC6 (0.37) | HDAC6 | |
| SCHEMBL6745468 | 0.71 | HDAC6 (0.43) | ICAM1HDAC6 | |
| SCHEMBL6747276 | 0.71 | HDAC6 (0.42) | ICAM1HDAC6 | |
| SCHEMBL8322460 | 0.70 | ICAM1 (0.40) | ICAM1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | UBE2M 4468/4885DCUN1D1 1830/4885ICAM1 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.