SCHEMBL6749694

SCHEMBL6749694

CCOc1ccc(C2(CCCC[Si](OC)(OC)OC)CCCCC2)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.33
SLC6A3 Q01959 3/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
GAA P10253 1/20 0.30
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11028664 0.85 SLC6A4 (0.37) SLC6A4SLC6A3
SCHEMBL6753578 0.84 SLC6A3 (0.36) SLC6A4SLC6A3ALDH1A1
SCHEMBL6751683 0.83 SLC6A4 (0.36) SLC6A4SLC6A3
SCHEMBL29214529 0.81 SLC6A3 (0.37) SLC6A4SLC6A3ALDH1A1APOBEC3G
SCHEMBL6752426 0.74
SCHEMBL3665645 0.70 APOBEC3G (0.36) MEN1KMT2AALDH1A1HPGDAPOBEC3G
SCHEMBL8963206 0.69 CNR1 (0.37) SLC6A4SLC6A3
SCHEMBL28984526 0.68 ALDH1A1 (0.39) SLC6A4SLC6A3ALDH1A1HPGD
SCHEMBL1243389 0.67 ALDH1A1 (0.36) SLC6A4SLC6A3MEN1KMT2AALDH1A1
SCHEMBL29016435 0.67 PDK2 (0.36) SLC6A4SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6703083-B2 LIQUID CRYSTALLINE COMPOUND HAVING A SIH3 GROUP AT AN END CHISSO CORPORATION (JP) 2004-03-09 US disclosed
US-20030168632-A1 Silicon compound, liquid cystal composition and liquid crystal display CHISSO PETROCHEMICAL CORPORATION (JP) 2003-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030168632-A1 Silicon compound, liquid cystal composition and liquid crystal display CLCN2, HCN2, PKD2 SLC6A4 2313/4885SLC6A3 1550/4885MEN1 310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.