Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.66 |
| ▸ | ECE1 | P42892 | 1/20 | 0.66 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.66 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.63 |
| ▸ | KDM1A | O60341 | 3/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | GCGR | P47871 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749878 | 1.00 | ECE2 (0.66) | ECE2ECE1MUS81SIRT1KDM1A | |
| SCHEMBL19283328 | 0.88 | KDM1A (0.70) | ECE2ECE1MUS81SIRT1KDM1A | |
| SCHEMBL19283329 | 0.88 | KDM1A (0.70) | ECE2ECE1MUS81SIRT1KDM1A | |
| SCHEMBL684875 | 0.87 | KDM1A (0.64) | SIRT1KDM1AMAOAMAOBNPC1 | |
| SCHEMBL6752033 | 0.85 | KDM1A (0.71) | ECE2ECE1MUS81SIRT1KDM1A | |
| SCHEMBL6568355 | 0.85 | KDM1A (0.69) | SIRT1KDM1AMAOAMAOBNPC1 | |
| SCHEMBL6752035 | 0.85 | KDM1A (0.71) | ECE2ECE1MUS81SIRT1KDM1A | |
| SCHEMBL8343578 | 0.85 | SIRT1 (0.85) | SIRT1KDM1AMAOAMAOBNPC1 | |
| SCHEMBL6568358 | 0.85 | KDM1A (0.69) | SIRT1KDM1AMAOAMAOBNPC1 | |
| SCHEMBL8343583 | 0.85 | SIRT1 (0.85) | SIRT1KDM1AMAOAMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110963-A1 | Novel hydrazones | ARPIDA AG (CH) | 2004-06-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110963-A1 | Novel hydrazones | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HK1, MPO | ECE2 526/4885ECE1 520/4885MUS81 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.