Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668003 | 1.00 | EPHX1 (0.37) | EPHX1GBA1HSD17B2LMNAMAPK1 | |
| SCHEMBL6667996 | 1.00 | EPHX1 (0.37) | EPHX1GBA1HSD17B2LMNAMAPK1 | |
| SCHEMBL11549245 | 0.78 | EPHX1 (0.39) | EPHX1GBA1HSD17B2LMNAMAPK1 | |
| SCHEMBL8882442 | 0.78 | EPHX1 (0.39) | EPHX1GBA1HSD17B2LMNAMAPK1 | |
| SCHEMBL8882439 | 0.78 | EPHX1 (0.39) | EPHX1GBA1HSD17B2LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL6666144 | 0.70 | EPHX1 (0.38) | EPHX1GBA1LMNAMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6666146 | 0.70 | EPHX1 (0.38) | EPHX1GBA1LMNAMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6683095 | 0.70 | EPHX1 (0.38) | EPHX1GBA1LMNAMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6671575 | 0.70 | EPHX1 (0.38) | EPHX1GBA1LMNAMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6671579 | 0.70 | EPHX1 (0.38) | EPHX1GBA1LMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831081-B2 | Herpes virus including simplex types 1 and 2, varicella zoster, human cytomegalovirus, Epstein-Barr and human 6, 7 and 8 | PHARMACIA & UPJOHN | 2004-12-14 | — | — | US | disclosed |
| US-20040110786-A1 | 4-Oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110786-A1 | 4-Oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents | ZC3HAV1, ZC3HAV1L, MAVS | EPHX1 2705/4885GBA1 891/4885HSD17B2 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.