SCHEMBL6750146

SCHEMBL6750146

Nc1nccn1-c1ncnc(Cl)n1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDR P35968 1/20 0.32
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25821884 0.70 LMNA (0.32)
SCHEMBL16203299 0.67 MAPT (0.51)
SCHEMBL17861349 0.64 PSEN1 (0.38) KDRHTT
SCHEMBL4947452 0.64 CSNK1A1 (0.46) HTT
SCHEMBL32909 0.63
SCHEMBL29370381 0.62
SCHEMBL10456578 0.62 ALDH1A1 (0.45)
SCHEMBL17844118 0.61 FGFR1 (0.49)
Hydrochloric Acid SCHEMBL27782884 0.61
SCHEMBL28330607 0.61 ALDH1A1 (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040116388-A1 triazine compoound inhibitors of enzymes that catalyze phosphoryl transfer and/or that bind ATP/GTP nucleotides AMGEN INC. 2004-06-17 US disclosed