Isopropylamine

Isopropylamine

SCHEMBL6750472

CC(C)N.O=C(O)CCCCCCC1=CC1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCD O00767 1/20 0.46
F13A1 P00488 3/20 0.44
RXFP1 Q9HBX9 2/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 5/20 0.42
TSHR P16473 5/20 0.41
LMNA P02545 3/20 0.41
NFKB1 P19838 1/20 0.41
PMP22 Q01453 1/20 0.41
S1PR2 O95136 1/20 0.40
S1PR1 P21453 1/20 0.40
S1PR3 Q99500 1/20 0.40
RECQL P46063 2/20 0.40
PRNP P04156 1/20 0.40
PPARG P37231 6/20 0.39
PPARD Q03181 6/20 0.39
PPARA Q07869 6/20 0.39
HDAC11 Q96DB2 5/20 0.39
GPR84 Q9NQS5 4/20 0.39
TLR2 O60603 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6751710 0.89 F13A1 (0.53) SCDF13A1RXFP1MAPTALDH1A1
SCHEMBL6748342 0.89 F13A1 (0.53) SCDF13A1RXFP1MAPTALDH1A1
Isopropylamine SCHEMBL16989789 0.85 GABRP (0.43) ALDH1A1S1PR2S1PR1S1PR3ALOX15
Azelaic Acid SCHEMBL29465682 0.79 TSHR (0.67) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL6750481 0.76 PAOX (0.45) SCDF13A1RXFP1MAPTALDH1A1
SCHEMBL28039677 0.74 SCD (0.47) SCDF13A1RXFP1MAPTALDH1A1
SCHEMBL1834739 0.72 TSHR (0.63) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL238692 0.72
Sebacic Acid SCHEMBL5875346 0.72 TSHR (0.63) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL31261412 0.71 F13A1 (0.47) SCDF13A1RXFP1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233669-B1 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES UNIV NORTH CAROLINA STATE (US) 2004-02-25 EP claimed
EP-1233669-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2002-08-28 EP claimed
US-6365549-B2 PRESERVATION NORTH CAROLINA STATE UNIVERSITY 2002-04-02 US claimed
US-20010019995-A1 Methods of blocking an ethylene response in plants using cyclopropene derivatives NORTH CAROLINA STATE UNIVERSITY 2001-09-06 US claimed
WO-2001037663-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2001-05-31 WO claimed
EP-1233669-B1 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES UNIV NORTH CAROLINA STATE (US) 2004-02-25 EP disclosed
EP-1233669-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2002-08-28 EP disclosed
US-6365549-B2 PRESERVATION NORTH CAROLINA STATE UNIVERSITY 2002-04-02 US disclosed
US-20010019995-A1 Methods of blocking an ethylene response in plants using cyclopropene derivatives NORTH CAROLINA STATE UNIVERSITY 2001-09-06 US disclosed
WO-2001037663-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2001-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010019995-A1 Methods of blocking an ethylene response in plants using cyclopropene derivatives PRUNE1, NOTUM, FAR1 SCD 112/4885F13A1 2555/4885RXFP1 1608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.