SCHEMBL6750489

SCHEMBL6750489

CCCCCOC(C)C1=CC1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.42
CNR2 P34972 5/20 0.39
CNR1 P21554 4/20 0.39
ALDH1A1 P00352 1/20 0.39
LPAR1 Q92633 4/20 0.33
LPAR3 Q9UBY5 4/20 0.33
LPAR2 Q9HBW0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3826529 0.79 DNM1 (0.35) DNM1CNR2CNR1ALDH1A1
SCHEMBL7977367 0.73 DNM1 (0.44) DNM1CNR2CNR1ALDH1A1LPAR1
SCHEMBL2745433 0.73 DNM1 (0.44) DNM1CNR2CNR1ALDH1A1LPAR1
SCHEMBL7995078 0.73 DNM1 (0.44) DNM1CNR2CNR1ALDH1A1LPAR1
SCHEMBL7994835 0.73 DNM1 (0.44) DNM1CNR2CNR1ALDH1A1LPAR1
SCHEMBL2744555 0.73 DNM1 (0.44) DNM1CNR2CNR1ALDH1A1LPAR1
SCHEMBL2745116 0.73 DNM1 (0.44) DNM1CNR2CNR1ALDH1A1LPAR1
SCHEMBL2744777 0.73 DNM1 (0.44) DNM1CNR2CNR1ALDH1A1LPAR1
SCHEMBL2744561 0.73 DNM1 (0.44) DNM1CNR2CNR1ALDH1A1LPAR1
SCHEMBL7977403 0.73 DNM1 (0.44) DNM1CNR2CNR1ALDH1A1LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233669-B1 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES UNIV NORTH CAROLINA STATE (US) 2004-02-25 EP claimed
EP-1233669-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2002-08-28 EP claimed
US-6365549-B2 PRESERVATION NORTH CAROLINA STATE UNIVERSITY 2002-04-02 US claimed
US-20010019995-A1 Methods of blocking an ethylene response in plants using cyclopropene derivatives NORTH CAROLINA STATE UNIVERSITY 2001-09-06 US claimed
WO-2001037663-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2001-05-31 WO claimed
EP-1233669-B1 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES UNIV NORTH CAROLINA STATE (US) 2004-02-25 EP disclosed
EP-1233669-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2002-08-28 EP disclosed
US-6365549-B2 PRESERVATION NORTH CAROLINA STATE UNIVERSITY 2002-04-02 US disclosed
US-20010019995-A1 Methods of blocking an ethylene response in plants using cyclopropene derivatives NORTH CAROLINA STATE UNIVERSITY 2001-09-06 US disclosed
WO-2001037663-A2 BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2001-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010019995-A1 Methods of blocking an ethylene response in plants using cyclopropene derivatives PRUNE1, NOTUM, FAR1 DNM1 2713/4885CNR2 336/4885CNR1 313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.