SCHEMBL6750647

SCHEMBL6750647

Cc1ccc2oc(=O)c(N)c(C)c2c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 11/20 0.40
KDM4E B2RXH2 9/20 0.40
ALDH1A1 P00352 6/20 0.40
MAPT P10636 5/20 0.39
HPGD P15428 4/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSD17B10 Q99714 4/20 0.36
USP2 O75604 1/20 0.36
MAPK1 P28482 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 2/20 0.35
MAOB P27338 2/20 0.34
ALDH2 P05091 1/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4812115 0.79 GAA (0.48) GAAKDM4EALDH1A1MAPTHPGD
SCHEMBL11230582 0.74 KDM4E (0.37) GAAKDM4EALDH1A1MAPTHPGD
SCHEMBL8128071 0.70 CDK9 (0.35) ALDH1A1ALDH2CYP1A2KMT2A
SCHEMBL15826632 0.69 KDM4E (0.46) GAAKDM4EALDH1A1MAPTHPGD
SCHEMBL29515065 0.69 GAA (0.69) GAAKDM4EALDH1A1MAPTHPGD
SCHEMBL565925 0.69 GAA (0.69) GAAKDM4EALDH1A1MAPTHPGD
SCHEMBL11308108 0.69 GAA (0.53) GAAKDM4EALDH1A1MAPTHPGD
Bromide SCHEMBL25420644 0.68 GAA (0.67) GAAKDM4EALDH1A1MAPTHPGD
Hydrochloric Acid SCHEMBL29609753 0.68 GAA (0.67) GAAKDM4EALDH1A1MAPTHPGD
SCHEMBL29104635 0.68 KDM4E (0.39) KDM4EALDH1A1MAPTHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6706341-B1 High opacity white thermal transfer ribbons containing glass particles INTERNATIONAL IMAGING MATERIALS INC. 2004-03-16 US disclosed
EP-1254782-A2 Thermal transfer ribbon International Imaging Materials Inc. (US) 2002-11-06 EP disclosed