Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5970712 | 0.84 | EDNRA (0.41) | KDM4EHSD17B10ALDH1A1HPGDRAB9A | |
| SCHEMBL4950101 | 0.80 | EDNRA (0.47) | KDM4EHSD17B10ALDH1A1HPGDRAB9A | |
| SCHEMBL28415710 | 0.76 | POLB (0.50) | ALDH1A1MCL1MEN1KMT2APOLB | |
| SCHEMBL29539987 | 0.71 | KCNH2 (0.60) | KDM4EHSD17B10ALDH1A1HPGDRAB9A | |
| SCHEMBL353910 | 0.70 | KCNH2 (0.58) | KDM4EHSD17B10ALDH1A1HPGDRAB9A | |
| SCHEMBL28286848 | 0.69 | MEN1 (0.42) | KDM4EHSD17B10ALDH1A1HPGDRAB9A | |
| SCHEMBL13787073 | 0.69 | CASP6 (0.62) | KDM4ERAB9ANPC1L3MBTL1KMT2A | |
| SCHEMBL8128071 | 0.69 | CDK9 (0.35) | ALDH1A1RAB9AMCL1KMT2A | |
| SCHEMBL5493547 | 0.68 | KDM4E (0.41) | KDM4EHSD17B10ALDH1A1HPGDRAB9A | |
| SCHEMBL6750647 | 0.68 | GAA (0.40) | KDM4EHSD17B10ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |