Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669924 | 0.91 | POLB (0.43) | ENPP2MEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL5672396 | 0.83 | HCRTR1 (0.43) | ENPP2MMP13MEN1KMT2AALDH1A1 | |
| SCHEMBL28757290 | 0.83 | LTA4H (0.41) | GRM2ENPP2MMP13TP53MEN1 | |
| SCHEMBL6750846 | 0.80 | SLC6A3 (0.41) | ENPP2 | |
| SCHEMBL6750833 | 0.77 | NPY1R (0.47) | GRM2MMP13TP53SMN1; SMN2HTR2C | |
| SCHEMBL3183974 | 0.70 | HTR2C (0.49) | HTR2CHTR2BLTA4H | |
| SCHEMBL5669916 | 0.68 | KCNH2 (0.41) | MEN1KMT2AALOX15L3MBTL1LTA4H | |
| SCHEMBL5398635 | 0.67 | KCNA5 (0.40) | SMN1; SMN2ALDH1A1ALOX15L3MBTL1LMNA | |
| SCHEMBL3177594 | 0.67 | GRM2 (0.60) | GRM2MMP13TP53SMN1; SMN2NPC1 | |
| SCHEMBL5884184 | 0.67 | PDE6D (0.46) | TP53KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1671387-A | Aryl substituted hydantoin compounds and their use as sodium channel blockers | EURO CELTIQUE SA (LU) | 2005-09-21 | — | — | CN | claimed |
| US-20040097569-A1 | Aryl substituted hydantoin compounds and their use as sodium channel blockers | EURO-CELTIQUE S.A. | 2004-05-20 | — | — | US | claimed |
| CN-1671387-A | Aryl substituted hydantoin compounds and their use as sodium channel blockers | EURO CELTIQUE SA (LU) | 2005-09-21 | — | — | CN | disclosed |
| US-20040097569-A1 | Aryl substituted hydantoin compounds and their use as sodium channel blockers | EURO-CELTIQUE S.A. | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097569-A1 | Aryl substituted hydantoin compounds and their use as sodium channel blockers | SCN1A, CACNA1S, SCN1B | GRM2 816/4885ENPP2 2941/4885MMP13 688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.