Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 1.00 |
| ▸ | TYR | P14679 | 1/20 | 0.79 |
| ▸ | BACE1 | P56817 | 2/20 | 0.78 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.76 |
| ▸ | BCHE | P06276 | 1/20 | 0.73 |
| ▸ | GUSB | P08236 | 1/20 | 0.73 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929576 | 1.00 | CHRNA7 (1.00) | CHRNA7TYRBACE1ABCG2BCHE | |
| SCHEMBL322102 | 1.00 | CHRNA7 (1.00) | CHRNA7TYRBACE1ABCG2BCHE | |
| SCHEMBL675095 | 0.88 | TYR (1.00) | CHRNA7TYRBACE1ABCG2CYP3A4 | |
| SCHEMBL675094 | 0.88 | TYR (1.00) | CHRNA7TYRBACE1ABCG2CYP3A4 | |
| SCHEMBL2977785 | 0.87 | CHRNA7 (1.00) | CHRNA7TYRBACE1BCHEGUSB | |
| SCHEMBL2977786 | 0.87 | CHRNA7 (1.00) | CHRNA7TYRBACE1BCHEGUSB | |
| SCHEMBL5426767 | 0.87 | CHRNA7 (1.00) | CHRNA7TYRBACE1BCHEGUSB | |
| SCHEMBL5426768 | 0.87 | CHRNA7 (1.00) | CHRNA7TYRBACE1BCHEGUSB | |
| SCHEMBL17975272 | 0.86 | CHRNA7 (0.76) | CHRNA7TYRBACE1ABCG2NR1H4 | |
| SCHEMBL130475 | 0.84 | BCHE (1.00) | CHRNA7BCHEGUSBCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2986136-B1 | COMPOSITION AND METHOD FOR PREVENTING, REDUCING, ALLEVIATING, OR TREATING IDIOPATHIC VOMITING | MARS INC (US) | 2020-08-12 | — | — | EP | claimed |
| EP-2986136-A1 | COMPOSITION AND METHOD FOR PREVENTING, REDUCING, ALLEVIATING, OR TREATING IDIOPATHIC VOMITING | The Iams Company (US) | 2016-02-24 | — | — | EP | claimed |
| CN-105188400-A | Compositions and methods for preventing, reducing, alleviating, or treating idiopathic vomiting | IAMS COMPANY | 2015-12-23 | — | — | CN | claimed |
| US-20140271949-A1 | Composition and Method for Preventing, Reducing, Alleviating or Treating Idiopathic Vomiting | THE IAMS COMPANY (US) | 2014-09-18 | — | — | US | claimed |
| WO-2014143539-A1 | COMPOSITION AND METHOD FOR PREVENTING, REDUCING, ALLEVIATING, OR TREATING IDIOPATHIC VOMITING | THE IAMS COMPANY (US) | 2014-09-18 | — | — | WO | claimed |
| CN-118105365-A | Use of a compound in the manufacture of a medicament for preventing or treating idiopathic vomiting in a companion animal | 马斯公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-105188400-B | Compositions and methods for preventing, alleviating or treating idiopathic vomiting | 马斯公司 | 2024-04-05 | — | — | CN | disclosed |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| EP-4228408-A1 | PEST REPELLENTS AND USES THEREOF | Sensorygen, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2023150072-A1 | COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER | SINCLAIR DAVID A (US) | 2023-08-10 | — | — | WO | disclosed |
| CN-109134205-B | Diarylalkanes as potent inhibitors of binuclear enzymes | 尤尼根公司 | 2022-07-19 | — | — | CN | disclosed |
| WO-2022082106-A1 | PEST REPELLENTS AND USES THEREOF | Sensorygen, Inc. (US) | 2022-04-21 | — | — | WO | disclosed |
| EP-1625150-B1 | TRIPEPTIDES AND DERIVATIVES THEREOF FOR COSMETIC APPLICATION IN ORDER TO IMPROVE SKIN STRUCTURE | PENTAPHARM AG (CH) | 2007-01-03 | — | — | EP | disclosed |
| WO-2006127539-A1 | USE OF CHALCONES FOR THE TREATMENT OF VIRAL DISORDERS | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| US-20060270614-A1 | Use of chalcones for the treatment of viral disorders | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2006-11-30 | — | — | US | disclosed |
| US-20060241094-A1 | Compositions that modulate the activity of estrogen receptors and estrogen-related receptors and methods for use | CITY OF HOPE | 2006-10-26 | — | — | US | disclosed |
| US-20060040876-A1 | Modulation of peroxisome proliferator-activated receptors | ABGENOMICS CORPORATION (TW) | 2006-02-23 | — | — | US | disclosed |
| EP-1611887-A2 | Modulation of peroxisome proliferator-activated receptors | Abgenomics Corporation (TW) | 2006-01-04 | — | — | EP | disclosed |
| WO-2005117849-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| US-20050267047-A1 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267047-A1 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | CHRNA7 2457/4885TYR 1/4885BACE1 1091/4885 |
| US-20060270614-A1 | Use of chalcones for the treatment of viral disorders | HAVCR2, HMGB3, EIF2AK2 | CHRNA7 4811/4885TYR 1529/4885BACE1 3952/4885 |
| US-20060241094-A1 | Compositions that modulate the activity of estrogen receptors and estrogen-related receptors and methods for use | ESR2, ESRRA, ESRRB | CHRNA7 272/4885TYR 3300/4885BACE1 2724/4885 |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | CHRNA7 2457/4885TYR 1/4885BACE1 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.