Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 9/20 | 1.00 |
| ▸ | TYR | P14679 | 2/20 | 0.79 |
| ▸ | BCHE | P06276 | 1/20 | 0.73 |
| ▸ | GUSB | P08236 | 1/20 | 0.73 |
| ▸ | MGAM | O43451 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | SI | P14410 | 1/20 | 0.68 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.68 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.65 |
| ▸ | CTSL | P07711 | 1/20 | 0.65 |
| ▸ | CTSB | P07858 | 1/20 | 0.65 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2977785 | 1.00 | CHRNA7 (1.00) | CHRNA7TYRBCHEGUSBMGAM | |
| SCHEMBL675095 | 0.88 | TYR (1.00) | CHRNA7TYRCAPN1CTSLCTSB | |
| SCHEMBL675094 | 0.88 | TYR (1.00) | CHRNA7TYRCAPN1CTSLCTSB | |
| SCHEMBL29929576 | 0.87 | CHRNA7 (1.00) | CHRNA7TYRBCHEGUSBCAPN1 | |
| SCHEMBL322102 | 0.87 | CHRNA7 (1.00) | CHRNA7TYRBCHEGUSBCAPN1 | |
| SCHEMBL633742 | 0.87 | CHRNA7 (1.00) | CHRNA7TYRBCHEGUSBCAPN1 | |
| SCHEMBL7198540 | 0.87 | CHRNA7 (0.77) | CHRNA7BCHEGUSBGAACAPN1 | |
| SCHEMBL7198542 | 0.87 | CHRNA7 (0.77) | CHRNA7BCHEGUSBGAACAPN1 | |
| SCHEMBL19236264 | 0.87 | CHRNA7 (1.00) | CHRNA7TYRGUSB | |
| SCHEMBL31398696 | 0.86 | CHRNA7 (0.76) | CHRNA7TYRBCHEGUSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001068-A | One-step green synthesis method for hydroxychalcone and flavanone | UNIV JIANGNAN | 2015-10-28 | — | — | CN | claimed |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20210085580-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN, INC. (US) | 2021-03-25 | — | — | US | disclosed |
| US-10857082-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2020-12-08 | — | — | US | disclosed |
| US-20200170907-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN, INC. (US) | 2020-06-04 | — | — | US | disclosed |
| US-10548825-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2020-02-04 | — | — | US | disclosed |
| EP-3015101-B1 | NON-PHOSPHOLIPID LIPOSOMES COMPRISING HYALURONIC ACID | PINSKY MARK A (US) | 2019-08-21 | — | — | EP | disclosed |
| CN-109134205-A | Diaryl alkane as binuclear enzymes potent inhibitor | 尤尼根公司 | 2019-01-04 | — | — | CN | disclosed |
| US-20160193126-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN INC (US) | 2016-07-07 | — | — | US | disclosed |
| CN-105001068-A | One-step green synthesis method for hydroxychalcone and flavanone | UNIV JIANGNAN | 2015-10-28 | — | — | CN | disclosed |
| US-7767661-B2 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| EP-1748767-A4 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN PHARMACEUTICALS INC (US) | 2008-12-24 | — | — | EP | disclosed |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | UNIGEN PHARMACEUTICALS, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| US-20070299410-A1 | SKIN TREATMENT ARTICLE | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2007-12-27 | — | — | US | disclosed |
| WO-2007084721-A2 | SKIN PROTECTION AND MOISTURIZING COMPOSITIONS AND METHODS | SAKURA PROPERTIES, LLC (US) | 2007-07-26 | — | — | WO | disclosed |
| EP-1748767-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | Unigen Pharmaceuticals, Inc. (US) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005117849-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| US-20050267047-A1 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-12-01 | — | — | US | disclosed |
| US-20040192649-A1 | Skin care compositions containing a sugar amine | BISSETT DONALD LYNN (US) | 2004-09-30 | — | — | US | disclosed |
| US-6294186-B1 | Antimicrobial compositions comprising a benzoic acid analog and a metal salt | PROCTER & GAMBLE COMPANY, THR | 2001-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200170907-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | TYR, DDT, HAAO | CHRNA7 2457/4885TYR 1/4885BCHE 141/4885 |
| US-10548825-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | CHRNA7 2457/4885TYR 1/4885BCHE 141/4885 |
| US-20050267047-A1 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | CHRNA7 2457/4885TYR 1/4885BCHE 141/4885 |
| US-20160193126-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | TYR, DDT, HAAO | CHRNA7 2457/4885TYR 1/4885BCHE 141/4885 |
| US-20040192649-A1 | Skin care compositions containing a sugar amine | RBP1, RBP4, RARB | CHRNA7 916/4885TYR 32/4885BCHE 362/4885 |
| US-10857082-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | CHRNA7 2457/4885TYR 1/4885BCHE 141/4885 |
| US-20210085580-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | TYR, DDT, HAAO | CHRNA7 2457/4885TYR 1/4885BCHE 141/4885 |
| US-20080132581-A1 | particularly tyrosinase; preventing and treating melanin overproduction; isolated from a plant family selected from the group consisting of Compositae, Fabaceae, Lauraceae, Leguminosae, Liliaceae, Loranthaceae, Moracea, and Myristicaceae | TYR, MAOA, CYP51A1 | CHRNA7 3754/4885TYR 1/4885BCHE 151/4885 |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | CHRNA7 2457/4885TYR 1/4885BCHE 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.