Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 19/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 19/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 19/20 | 0.48 |
| ▸ | CDK2 | P24941 | 19/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 19/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751475 | 1.00 | CCNE2 (0.48) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6753817 | 0.88 | CDK2 (0.45) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6753818 | 0.88 | CDK2 (0.45) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6753756 | 0.86 | KMT2A (0.35) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL4372906 | 0.81 | CDK2 (0.54) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL4372901 | 0.81 | CDK2 (0.54) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL4375080 | 0.78 | CDK2 (0.56) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL4377640 | 0.78 | CDK2 (0.56) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL30848442 | 0.72 | CCNE2 (0.73) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL30848443 | 0.72 | CCNE2 (0.73) | CCNE2CCNA2CCNE1CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377579-A2 | ACYL AND SULFONYL DERIVATIVES OF 6,9-DISUBSTITUTED 2-(TRANS-1,4-DIAMINOCYCLOHEXYL)-PURINES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS | Aventis Pharmaceuticals Inc. (US) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002042303-A2 | ACYL AND SULFONYL DERIVATIVES OF 6,9-DISUBSTITUTED 2-(TRANS-1,4-DIAMINOCYCLOHEXYL)-PURINES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS | AVENTIS PHARMACEUTICALS INC. (US) | 2002-05-30 | — | — | WO | disclosed |