Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 12/20 | 0.62 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.48 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069436 | 0.90 | TYMP (0.62) | TYMPTK1P2RY6P2RY14 | |
| SCHEMBL13714472 | 0.90 | TYMP (0.62) | TYMPTK1P2RY6P2RY14 | |
| SCHEMBL6246850 | 0.90 | TYMP (0.62) | TYMPTK1P2RY6P2RY14 | |
| SCHEMBL9710318 | 0.90 | TYMP (0.62) | TYMPTK1P2RY6P2RY14 | |
| SCHEMBL3069438 | 0.90 | TYMP (0.62) | TYMPTK1P2RY6P2RY14 | |
| SCHEMBL13205014 | 0.90 | TYMP (0.62) | TYMPTK1P2RY6P2RY14 | |
| SCHEMBL15974161 | 0.90 | TYMP (0.62) | TYMPTK1P2RY6P2RY14 | |
| SCHEMBL8197884 | 0.90 | TYMP (0.62) | TYMPP2RY6P2RY14P2RY2 | |
| SCHEMBL8534788 | 0.90 | TYMP (0.62) | TYMPP2RY6P2RY14 | |
| SCHEMBL8534790 | 0.90 | TYMP (0.62) | TYMPP2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419169-A1 | ANTISENSE MODULATION OF COREST EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1417216-A2 | ANTISENSE MODULATION OF BCL2-ASSOCIATED X PROTEIN EXPRESSION | ISIS Pharmaceuticals, Inc. (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-1290204-A1 | ANTISENSE MODULATION OF C/EBP ALPHA EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2003011890-A1 | ANTISENSE MODULATION OF COREST EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2003-02-13 | — | — | WO | disclosed |
| WO-2003008543-A2 | ANTISENSE MODULATION OF BCL2-ASSOCIATED X PROTEIN EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2003-01-30 | — | — | WO | disclosed |
| WO-2001096586-A1 | ANTISENSE MODULATION OF C/EBP ALPHA EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2001-12-20 | — | — | WO | disclosed |