Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 2/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747802 | 0.89 | HTT (0.61) | HTTSMN1; SMN2NPC1RAB9APDE4B | |
| SCHEMBL6749252 | 0.89 | SMN1; SMN2 (0.60) | HTTSMN1; SMN2NPC1RAB9APDE4B | |
| SCHEMBL15743158 | 0.86 | CHRM4 (0.46) | RAB9ACHRM4ALDH1A1 | |
| SCHEMBL7502284 | 0.84 | BCL9 (0.62) | HTTSMN1; SMN2NPC1RAB9APDE4B | |
| SCHEMBL2384566 | 0.84 | SMN1; SMN2 (0.62) | HTTSMN1; SMN2NPC1RAB9APDE4B | |
| SCHEMBL15710267 | 0.83 | GPR119 (0.51) | SMN1; SMN2PDE4BALDH1A1GAAMAPT | |
| SCHEMBL4035554 | 0.83 | SMN1; SMN2 (0.72) | HTTSMN1; SMN2NPC1RAB9APDE4B | |
| SCHEMBL6745682 | 0.83 | SMN1; SMN2 (0.58) | HTTSMN1; SMN2NPC1RAB9APDE4B | |
| SCHEMBL31198753 | 0.82 | SMN1; SMN2 (0.60) | HTTSMN1; SMN2NPC1RAB9APDE4B | |
| SCHEMBL31173378 | 0.81 | HTT (0.48) | HTTSMN1; SMN2NPC1RAB9APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | HTT 2395/4885SMN1; SMN2 4491/4885NPC1 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.