Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055368 | 0.85 | FLT3 (0.56) | FLT3ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL4060138 | 0.83 | FLT3 (0.53) | FLT3ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL4599061 | 0.81 | ALDH1A1 (0.50) | FLT3ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL14432867 | 0.80 | FLT3 (0.65) | FLT3ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL5158485 | 0.79 | FLT3 (0.62) | FLT3ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL3032755 | 0.77 | FLT3 (0.61) | FLT3ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL10313745 | 0.75 | FLT3 (0.67) | FLT3ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL28117952 | 0.75 | FLT3 (0.67) | FLT3ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL10155752 | 0.75 | FLT3 (0.67) | FLT3ALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL5160482 | 0.75 | FLT3 (0.57) | FLT3ALDH1A1MAPTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082464-A1 | Complex polymerization catalysts for the homopolymerization of ethylene and for the copolymerization of ethylene | POLIMERI EUROPA S.P.A. (IT) | 2004-04-29 | — | — | US | disclosed |
| EP-1268500-B1 | COMPLEX POLYMERIZATION CATALYSTS FOR THE HOMOPOLYMERIZATION OF ETHYLENE AND FOR THE COPOLYMERIZATION OF ETHYLENE | POLIMERI EUROPA SPA (IT) | 2003-10-01 | — | — | EP | disclosed |
| EP-1312622-A1 | Process for the preparation of linear or branched 1,4-cis polybutadiene | ENI S.p.A. (IT) | 2003-05-21 | — | — | EP | disclosed |
| EP-1268500-A1 | COMPLEX POLYMERIZATION CATALYSTS FOR THE HOMOPOLYMERIZATION OF ETHYLENE AND FOR THE COPOLYMERIZATION OF ETHYLENE | Polimeri Europa S.p.A. (IT) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074831-A1 | COMPLEX POLYMERIZATION CATALYSTS FOR THE HOMOPOLYMERIZATION OF ETHYLENE AND FOR THE COPOLYMERIZATION OF ETHYLENE | POLIMERI EUROPA S.P.A. (IT) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082464-A1 | Complex polymerization catalysts for the homopolymerization of ethylene and for the copolymerization of ethylene | ETV6, MVD, ELL | FLT3 3738/4885ALDH1A1 2491/4885MAPT 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.