Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10313745 | 0.85 | FLT3 (0.67) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL10155752 | 0.85 | FLT3 (0.67) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL14432867 | 0.84 | FLT3 (0.65) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL243970 | 0.84 | FLT3 (0.65) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL6032072 | 0.84 | FLT3 (0.65) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL5158485 | 0.82 | FLT3 (0.62) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL2560643 | 0.82 | FLT3 (0.62) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL5309787 | 0.81 | FLT3 (0.71) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL2327568 | 0.81 | LMNA (0.66) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL3032755 | 0.81 | FLT3 (0.61) | FLT3NPC1RAB9AMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817483-B | A kind of pair of carbonyl Benzazole compounds and its synthetic method | 华东师范大学 | 2017-10-31 | — | — | CN | disclosed |
| CN-104177241-B | Alkynyl diketone compound and synthetic method thereof | 华东师范大学 | 2017-01-11 | — | — | CN | disclosed |