SCHEMBL675338

SCHEMBL675338

OC(c1ccccc1)(c1ccc(Cl)cc1)c1ccccc1Cl

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.71
CYP3A5 P20815 3/20 0.71
CYP19A1 P11511 11/20 0.71
KCNN4 O15554 1/20 0.50
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
ADRA1A P35348 1/20 0.45
OPRK1 P41145 1/20 0.45
KCNH2 Q12809 1/20 0.45
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42
BCL2 P10415 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2131459 0.92 CYP3A4 (0.60) CYP3A4CYP3A5CYP19A1KCNN4HTR2A
SCHEMBL30114522 0.92 CYP3A4 (0.60) CYP3A4CYP3A5CYP19A1KCNN4HTR2A
SCHEMBL6369689 0.88 KCNN4 (0.57) CYP3A4CYP3A5CYP19A1KCNN4HTR2A
SCHEMBL4466320 0.87 CYP3A4 (0.56) CYP3A4CYP3A5CYP19A1KCNN4HTR2A
SCHEMBL14156831 0.85 CYP3A4 (0.55) CYP3A4CYP3A5CYP19A1KCNN4HTR2A
SCHEMBL6904433 0.84 CYP3A4 (1.00) CYP3A4CYP3A5CYP19A1
SCHEMBL2391264 0.83 CYP19A1 (0.62) CYP3A4CYP3A5CYP19A1MEN1KMT2A
SCHEMBL2389063 0.83 CYP19A1 (0.62) CYP3A4CYP3A5CYP19A1MEN1KMT2A
Fenarimol SCHEMBL6577573 0.83 CYP19A1 (1.00) CYP3A4CYP3A5CYP19A1
Fenarimol SCHEMBL42209 0.83 CYP19A1 (1.00) CYP3A4CYP3A5CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9918474-B2 Agents for combating plant pests BAYER INTELLECTUAL PROPERTY GMBH (DE) 2018-03-20 US disclosed
US-9918474-B2 Agents for combating plant pests BAYER INTELLECTUAL PROPERTY GMBH (DE) 2018-03-20 US disclosed
US-20170188582-A1 Agents for Combating Plant Pests BAYER AKTIENGESELLSCHAFT (DE) 2017-07-06 US disclosed
US-20170188582-A1 Agents for Combating Plant Pests BAYER AKTIENGESELLSCHAFT (DE) 2017-07-06 US disclosed
US-9504254-B2 Agents for combating plant pests BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-11-29 US disclosed
US-9504254-B2 Agents for combating plant pests BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-11-29 US disclosed
US-8853126-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2014-10-07 US disclosed
US-8853126-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2014-10-07 US disclosed
US-20140107112-A1 Agents for Combating Plant Pests BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-04-17 US disclosed
US-20140107112-A1 Agents for Combating Plant Pests BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-04-17 US disclosed
US-7361673-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2008-04-22 US disclosed
US-7361673-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2008-04-22 US disclosed
US-20070203208-A1 comprises a mixture of insecticides and fungicides; synergistic BAYER INTELLECTUAL PROPERTY GMBH (DE) 2007-08-30 US disclosed
US-20070203208-A1 comprises a mixture of insecticides and fungicides; synergistic BAYER INTELLECTUAL PROPERTY GMBH (DE) 2007-08-30 US disclosed
US-7232840-B2 Agents for combating plant pests BAYER CROPSCIENCE AG (DE) 2007-06-19 US disclosed
US-7232840-B2 Agents for combating plant pests BAYER CROPSCIENCE AG (DE) 2007-06-19 US disclosed
US-20070043086-A1 synergistic mixture of (2-chloropyridine)-(2-cyanoiminothiazolidine)-methyl and azolo-fingicidal compounds; fungicides, herbicides and insecticide; controlling plant pests ERDELEN CHRISTOPH 2007-02-22 US disclosed
US-20070043086-A1 synergistic mixture of (2-chloropyridine)-(2-cyanoiminothiazolidine)-methyl and azolo-fingicidal compounds; fungicides, herbicides and insecticide; controlling plant pests ERDELEN CHRISTOPH 2007-02-22 US disclosed
US-7179814-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2007-02-20 US disclosed
US-7179814-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2007-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140107112-A1 Agents for Combating Plant Pests DDT, CYP51A1, AADAC CYP3A4 624/4885CYP3A5 157/4885CYP19A1 1235/4885
US-20070043086-A1 synergistic mixture of (2-chloropyridine)-(2-cyanoiminothiazolidine)-methyl and azolo-fingicidal compounds; fungicides, herbicides and insecticide; controlling plant pests SPHK2, GRM2, DHFR CYP3A4 1021/4885CYP3A5 877/4885CYP19A1 2557/4885
US-20070203208-A1 comprises a mixture of insecticides and fungicides; synergistic DDT, CYP51A1, CYP4Z1 CYP3A4 18/4885CYP3A5 15/4885CYP19A1 41/4885
US-20170188582-A1 Agents for Combating Plant Pests DDT, CYP51A1, AADAC CYP3A4 624/4885CYP3A5 157/4885CYP19A1 1235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.