Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289767 | 0.85 | CYP2A6 (0.56) | CES1MAOBCYP2A6MAOANOTUM | |
| SCHEMBL5508289 | 0.81 | CES1 (0.71) | CES1MAOBCYP2A6MAOAALDH1A1 | |
| SCHEMBL24893653 | 0.81 | CES1 (0.56) | CES1MAOBCYP2A6MAOASETD7 | |
| Dihydrophenanthrene SCHEMBL29404495 | 0.80 | CES1 (0.68) | CES1MAOBCYP2A6MAOASETD7 | |
| Dihydrophenanthrene SCHEMBL155991 | 0.80 | CES1 (0.68) | CES1MAOBCYP2A6MAOASETD7 | |
| Dihydrophenanthrene SCHEMBL30297028 | 0.80 | CES1 (0.68) | CES1MAOBCYP2A6MAOASETD7 | |
| SCHEMBL30436624 | 0.77 | CES1 (0.65) | CES1MAOBCYP2A6MAOASETD7 | |
| Dihydrophenanthrene SCHEMBL28876918 | 0.77 | CES1 (0.65) | CES1MAOBCYP2A6MAOASETD7 | |
| Dihydrophenanthrene SCHEMBL28858771 | 0.77 | CES1 (0.65) | CES1MAOBCYP2A6MAOASETD7 | |
| SCHEMBL18938578 | 0.75 | CES1 (0.62) | CES1MAOBCYP2A6MAOASETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292448-B | Indanone imine derivative and preparation method and application thereof | 中山大学 | 2022-06-28 | — | — | CN | claimed |
| CN-113292448-A | Indanone imine derivative and preparation method and application thereof | 中山大学 | 2021-08-24 | — | — | CN | claimed |
| CN-113292448-B | Indanone imine derivative and preparation method and application thereof | 中山大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113292448-B | Indanone imine derivative and preparation method and application thereof | 中山大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113292448-B | Indanone imine derivative and preparation method and application thereof | 中山大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113292448-A | Indanone imine derivative and preparation method and application thereof | 中山大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-113292448-A | Indanone imine derivative and preparation method and application thereof | 中山大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-113292448-A | Indanone imine derivative and preparation method and application thereof | 中山大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-104870435-B | Aryl and heteroaryl-condensed lactams | 辉瑞大药厂 | 2016-12-07 | — | — | CN | disclosed |
| CN-105530923-A | Aryl ethers and their use | PELOTON THERAPEUTICS INC | 2016-04-27 | — | — | CN | disclosed |
| CN-104870435-A | Aryl and heteroaryl fused lactams | PFIZER | 2015-08-26 | — | — | CN | disclosed |
| CN-103086834-B | Preparation method of biaryl indene compounds | SHANGHAI RES INST CHEMICAL IND | 2015-05-27 | — | — | CN | disclosed |
| CN-103086834-A | Preparation method of biaryl indene compounds | SHANGHAI RES INST CHEMICAL IND | 2013-05-08 | — | — | CN | disclosed |
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | UNIVERSITEIT GENT (BE) | 2012-03-29 | — | — | US | disclosed |
| EP-1795344-A1 | Lithographic printing plate precursor and lithographic printing method | FUJIFILM Corporation (JP) | 2007-06-13 | — | — | EP | disclosed |
| JP-2004087550-A | PRINTED WIRING BOARD | TOPPAN PRINTING CO LTD | 2004-03-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | IDH2, CYCS, NAPRT | CES1 4157/4885MAOB 709/4885CYP2A6 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.