Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753858 | 0.85 | CES1 (0.54) | CYP2A6MAOAMAOBTSHRL3MBTL1 | |
| SCHEMBL3103992 | 0.82 | CYP2A6 (0.68) | CYP2A6MAOAMAOBTSHRL3MBTL1 | |
| SCHEMBL30505637 | 0.82 | CYP2A6 (0.68) | CYP2A6MAOAMAOBTSHRL3MBTL1 | |
| SCHEMBL30436320 | 0.79 | CYP2A6 (0.65) | CYP2A6MAOAMAOBTSHRL3MBTL1 | |
| SCHEMBL9652088 | 0.79 | CYP2A6 (0.65) | CYP2A6MAOAMAOBTSHRL3MBTL1 | |
| SCHEMBL31430380 | 0.76 | TSHR (0.71) | CYP2A6MAOAMAOBTSHRL3MBTL1 | |
| SCHEMBL568779 | 0.76 | TSHR (0.71) | CYP2A6MAOAMAOBTSHRL3MBTL1 | |
| SCHEMBL7102942 | 0.74 | MEN1 (0.36) | CYP2A6MAOAMAOBTSHRL3MBTL1 | |
| SCHEMBL31135519 | 0.74 | TSHR (0.67) | CYP2A6MAOAMAOBTSHRL3MBTL1 | |
| SCHEMBL31621255 | 0.74 | TSHR (0.67) | CYP2A6MAOAMAOBTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-213049951-U | Tetrahydroimine dust recovery device | 河南源博新材料有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-116655582-B | Synthesis method and application of sanguinarine intermediate compound bromo-compound | 宁波九胜创新医药科技有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-116444478-B | Preparation method and application of aromatic benzo [ c ] phenanthridine alkaloid intermediate compound | 宁波九胜创新医药科技有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-116655582-A | Synthesis method and application of sanguinarine intermediate compound bromo-compound | 宁波九胜创新医药科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116444478-A | Preparation method and application of aromatic benzo [ c ] phenanthridine alkaloid intermediate compound | 宁波九胜创新医药科技有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-109879792-B | Polysubstituted isoindole compound and preparation method thereof | 广东工业大学 | 2022-06-24 | — | — | CN | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| EP-3216787-B1 | INTERMEDIATES FOR THE PREPARATION OF MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3561876-A1 | DISPLAY | Novaled GmbH (DE) | 2019-10-30 | — | — | EP | disclosed |
| US-20090298876-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-12-03 | — | — | US | disclosed |
| EP-2116527-A1 | OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, METHOD FOR PRODUCTION OF THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT | FUJIFILM Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-20090246820-A1 | COMPOUNDS USEFUL IN CFTR ASSAYS AND METHODS THEREWITH | VERTEX PHARMACEUTICALS INCORPORATED | 2009-10-01 | — | — | US | disclosed |
| US-20090227797-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-09-10 | — | — | US | disclosed |
| US-7495103-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-03-20 | — | — | US | disclosed |
| US-4088786-A | Method for utilizing tetrahydro-4-imino-1-naphthylureas as growth promoting agents for animals | AMERICAN CYANAMID COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4076952-A | ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4072711-A | ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
| US-4041070-A | ANIMAL GROWTH PROMOTERS, ENHANCING FEED EFFICIENCY | AMERICAN CYANAMID COMPANY (US) | 1977-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227797-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | CYP2A6 1793/4885MAOA 3867/4885MAOB 2865/4885 |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | CYP2A6 1793/4885MAOA 3867/4885MAOB 2865/4885 |
| US-20090298876-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | CYP2A6 1793/4885MAOA 3867/4885MAOB 2865/4885 |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | CFTR, ABCB1, ABCC1 | CYP2A6 3185/4885MAOA 4364/4885MAOB 3796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.