SCHEMBL6753905

SCHEMBL6753905

CC(=O)C(F)(F)C(=O)Nc1ccccc1F

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 2/20 0.64
PDK2 Q15119 2/20 0.64
PDK3 Q15120 2/20 0.64
PDK4 Q16654 2/20 0.64
RAB9A P51151 5/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
NPC1 O15118 3/20 0.56
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 1/20 0.53
ALOX12 P18054 1/20 0.53
HTT P42858 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
LMNA P02545 3/20 0.46
POLB P06746 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1576313 0.82 PDK1 (0.67) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL7089699 0.80 RAB9A (0.71) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL18458382 0.79 PDK1 (0.68) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL6350100 0.78 PDK1 (1.00) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL29408738 0.77 RAB9A (0.69) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL1430533 0.77 RAB9A (0.69) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL22472038 0.77 RAB9A (0.62) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL7098684 0.74 RAB9A (0.64) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL2794382 0.74 RAB9A (0.69) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL6850971 0.73 RAB9A (0.75) PDK1PDK2PDK3PDK4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6749908-B2 LAMINATES/TRANSPARENCIES FOR OVERHEAD PROJECTORS FUJI PHOTO FILM CO., LTD. (JP) 2004-06-15 US disclosed
US-20030114305-A1 Multicolor heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-06-19 US disclosed
US-6017672-A MIXTURE OF DIAZONIUM SALT HAVING ABSORPTION WAVELENGTH SHORTER THAN 350 NANOMETERS AND A THERMALLY REACTIVE COUPLER CONTAINED WITHIN RECORDING LAYER COATED ONTO SUPPORT; STORAGE STABILITY, PHOTOSTABILITY, HIGH COLOR DENSITY FUJI PHOTO FILM CO., LTD. (JP) 2000-01-25 US disclosed
WO-1995032952-A1 PROCESS FOR THE PREPARATION OF 3-ARYLURACILS CIBA-GEIGY AG (CH) 1995-12-07 WO disclosed