Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453959 | 0.75 | MEN1 (0.53) | L3MBTL1MEN1KMT2APKMCTDSP1 | |
| SCHEMBL3966889 | 0.75 | MEN1 (0.53) | L3MBTL1MEN1KMT2APKMCTDSP1 | |
| SCHEMBL8042705 | 0.74 | SLC6A3 (0.43) | MEN1KMT2APKMCTDSP1SMN1; SMN2 | |
| SCHEMBL6756588 | 0.74 | DPP4 (0.42) | MEN1KMT2ADPP4 | |
| SCHEMBL8046455 | 0.68 | SLC6A3 (0.38) | DPP4 | |
| SCHEMBL11715973 | 0.67 | FFAR1 (0.44) | L3MBTL1MEN1KMT2APKMCTDSP1 | |
| SCHEMBL2467478 | 0.66 | MEN1 (0.53) | L3MBTL1MEN1KMT2APKMCTDSP1 | |
| SCHEMBL6756372 | 0.66 | GBA1 (0.43) | SMN1; SMN2 | |
| SCHEMBL2886678 | 0.66 | TSHR (0.40) | SMN1; SMN2 | |
| SCHEMBL29097501 | 0.66 | SLC6A3 (0.40) | MEN1KMT2APKMCTDSP1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716491-B2 | BASED ON MIXTURE OF POLAR COMPOUNDS OF POSITIVE DIELECTRIC ANISOTROPY; FOR USE IN MATRIX LIQUID CRYSTAL AND TWISTED/SUPERTWISTED NEMATIC CELLS | MERCK PATENT GMBH (DE) | 2004-04-06 | — | — | US | disclosed |
| US-20020030180-A1 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2002-03-14 | — | — | US | disclosed |