Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CFTR | P13569 | 5/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362934 | 0.79 | GAA (0.70) | GAAPOLBGLATSHRCFTR | |
| SCHEMBL15695597 | 0.78 | TAAR1 (0.55) | GAAPOLBTSHRCFTRTAAR1 | |
| SCHEMBL17451259 | 0.78 | TSHR (1.00) | GAAPOLBGLATSHRKDM4E | |
| SCHEMBL29350569 | 0.78 | TSHR (1.00) | GAAPOLBGLATSHRKDM4E | |
| SCHEMBL109685 | 0.78 | TSHR (1.00) | GAAPOLBGLATSHRKDM4E | |
| SCHEMBL6873928 | 0.77 | TAAR1 (0.53) | GAAPOLBCFTRTAAR1ADORA2A | |
| SCHEMBL16401835 | 0.77 | PIK3R1 (0.56) | GAAPOLBTSHRCFTRPIK3R1 | |
| Hydrochloric Acid SCHEMBL8642589 | 0.76 | TSHR (0.95) | GAAPOLBGLATSHRKDM4E | |
| Water SCHEMBL20506731 | 0.76 | TSHR (0.95) | GAAPOLBGLATSHRKDM4E | |
| Ammonia Solution, Strong SCHEMBL6812982 | 0.76 | TSHR (0.95) | GAAPOLBGLATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729519-B1 | AROMATIC POLYAMIDE FILMS FOR SOLVENT RESISTANT FLEXIBLE SUBSTRATES | AKRON POLYMER SYSTEMS INC (US) | 2019-05-15 | — | — | EP | claimed |
| EP-1399163-A2 | COMPOUNDS, METHODS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF BOVINE VIRAL DIARRHEA VIRUS (BVDV) INFECTION AND HEPATITIS C VIRUS (HCV) INFECTION | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002055025-A2 | COMPOUNDS, METHODS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF BOVINE VIRAL DIARRHEA VIRUS (BVDV) INFECTION AND HEPATITIS C VIRUS (HCV) INFECTION | UNIV NORTH CAROLINA (US) | 2002-07-18 | — | — | WO | disclosed |