Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.64 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.64 |
| ▸ | MMP1 | P03956 | 4/20 | 0.64 |
| ▸ | MMP2 | P08253 | 4/20 | 0.64 |
| ▸ | MMP9 | P14780 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754380 | 1.00 | TRPV1 (0.73) | TRPV1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23547197 | 1.00 | TRPV1 (0.73) | TRPV1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6860426 | 0.88 | TRPV1 (0.76) | TRPV1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6860429 | 0.88 | TRPV1 (0.76) | TRPV1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5448327 | 0.88 | HPGD (0.79) | TRPV1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5448329 | 0.88 | HPGD (0.79) | TRPV1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8065947 | 0.86 | MEN1 (0.84) | TRPV1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8065945 | 0.86 | MEN1 (0.84) | TRPV1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13675641 | 0.85 | KMT2A (0.67) | TRPV1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10823954 | 0.85 | ALDH1A1 (0.63) | TRPV1KMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650986-B | Cinnamoyl amino pyrazolo [3,4-d ] pyrimidine compound, and preparation and application thereof | 浙江工业大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-115286589-B | Cinnamoyl tetrazine compound, and preparation and application thereof | 浙江工业大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-115650986-A | Cinnamyl amino pyrazolo [3,4-d ] pyrimidine compound and preparation and application thereof | 浙江工业大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-115286589-A | Cinnamoyl tetrazine compound and preparation and application thereof | 浙江工业大学 | 2022-11-04 | — | — | CN | disclosed |
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | H1-2, H1-0, H1-3 | TRPV1 1618/4885KMT2A 130/4885MEN1 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.