Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753476 | 0.84 | SMN1; SMN2 (0.47) | ALDH1A1KDM4EGAAHPGDL3MBTL1 | |
| SCHEMBL10362962 | 0.80 | KDM4E (0.62) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL10362966 | 0.79 | KDM4E (0.46) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL6754552 | 0.79 | KDM4E (0.51) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL10362803 | 0.79 | CA12 (0.54) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL25223019 | 0.78 | KDM4E (0.50) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL6755336 | 0.78 | KDM4E (0.50) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL3994731 | 0.77 | GAA (0.52) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL6754531 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL6752153 | 0.75 | KDM4E (0.46) | ALDH1A1KDM4EGAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706528-B2 | DETECTING MAGNESIUM ION WITH A CARBOXY-QUINOLIZINE COMPOUND TO FORM A COMPLEX AND DETECTING FLUORESCENCE IN SAID COMPLEX; FOR DIAGNOSIS OF CARDIOVASCULAR DISEASES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2004-03-16 | — | — | US | disclosed |
| US-20020031834-A1 | Fluorescent magnesium indicators | THE GOVERNMENT OF THE UNITED STATES | 2002-03-14 | — | — | US | disclosed |