Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | GLA | P06280 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362962 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL6754552 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL10362803 | 0.80 | CA12 (0.54) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL25223019 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL6755336 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL6754479 | 0.75 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL8565982 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL4616746 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL6752047 | 0.73 | KDM4E (0.43) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL8136267 | 0.72 | KDM4E (0.45) | KDM4EALDH1A1HPGDGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706528-B2 | DETECTING MAGNESIUM ION WITH A CARBOXY-QUINOLIZINE COMPOUND TO FORM A COMPLEX AND DETECTING FLUORESCENCE IN SAID COMPLEX; FOR DIAGNOSIS OF CARDIOVASCULAR DISEASES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2004-03-16 | — | — | US | disclosed |
| US-20020031834-A1 | Fluorescent magnesium indicators | THE GOVERNMENT OF THE UNITED STATES | 2002-03-14 | — | — | US | disclosed |