Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24804024 | 0.79 | CYP1A2 (0.47) | GAACYP1A2RXFP1NQO2ABCB11 | |
| SCHEMBL24102936 | 0.77 | GAA (0.46) | GAACYP1A2RXFP1NQO2ABCB11 | |
| SCHEMBL25134416 | 0.76 | GAA (0.44) | GAACYP1A2RXFP1NQO2ABCB11 | |
| SCHEMBL30265966 | 0.74 | GAA (0.46) | GAACYP1A2RXFP1NQO2ABCB11 | |
| SCHEMBL5729594 | 0.74 | GAA (0.46) | GAACYP1A2RXFP1NQO2ABCB11 | |
| SCHEMBL1650595 | 0.71 | CYP1A2 (0.55) | GAACYP1A2RXFP1NQO2ABCB11 | |
| SCHEMBL8230643 | 0.70 | DAO (0.56) | GAACYP1A2RXFP1NQO2ALDH1A1 | |
| SCHEMBL29713806 | 0.70 | DAO (0.56) | GAACYP1A2RXFP1NQO2ALDH1A1 | |
| SCHEMBL4898909 | 0.69 | GAA (0.38) | GAACYP1A2RXFP1NQO2ABCB11 | |
| SCHEMBL933745 | 0.67 | GAA (0.50) | GAACYP1A2RXFP1NQO2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092750-A1 | 2-methylindole-4-acetic acid, process for producing the same, and process for producing intermediate therefor | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1367050-A1 | 2-METHYLINDOLE-4-ACETIC ACID, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING INTERMEDIATE THEREFOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092750-A1 | 2-methylindole-4-acetic acid, process for producing the same, and process for producing intermediate therefor | TPH2, ALDH7A1, IDO1 | GAA 3213/4885CYP1A2 59/4885RXFP1 756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.