Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729594 | 1.00 | GAA (0.46) | GAARXFP1CYP1A2NQO2PRKCQ | |
| SCHEMBL18000148 | 0.81 | GAA (0.46) | GAARXFP1CYP1A2NQO2ALDH1A1 | |
| SCHEMBL15829328 | 0.81 | NR3C1 (0.39) | GAACYP1A2DYRK1ACLK1TSHR | |
| SCHEMBL24453539 | 0.79 | NR3C1 (0.45) | CYP1A2DYRK1ACLK1TSHRIMPDH2 | |
| SCHEMBL28813546 | 0.78 | DYRK1A (0.41) | DYRK1ACLK1IMPDH2IMPDH1MAP2K1 | |
| SCHEMBL12778104 | 0.78 | DYRK1A (0.41) | DYRK1ACLK1IMPDH2IMPDH1MAP2K1 | |
| SCHEMBL16380972 | 0.77 | DYRK1A (0.39) | GAADYRK1ACLK1TSHRIMPDH2 | |
| SCHEMBL24037986 | 0.76 | MAOA (0.40) | GAARXFP1CYP1A2NQO2PRKCQ | |
| SCHEMBL2430502 | 0.75 | MAOA (0.47) | GAARXFP1CYP1A2NQO2PRKCQ | |
| SCHEMBL12803649 | 0.75 | KEAP1 (0.44) | GAARXFP1CYP1A2NQO2PRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074096-A1 | P97 (VCP) ATPASE INHIBITORS | Turbine Simulated Cell Technologies Ltd (GB) | 2025-04-10 | — | — | WO | disclosed |
| WO-2025014963-A1 | INHIBITORS OF P97 PROTEIN AND METHODS OF USE | GANDEEVA THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |
| WO-2023012153-A1 | VALOSIN-CONTAINING PROTEIN (VCP/P97) INHIBITORS | PHOREMOST LIMITED (GB) | 2023-02-09 | — | — | WO | disclosed |