Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6758117 | 0.94 | HRH4 (0.48) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL6759310 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL6758252 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL6757422 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL6755065 | 0.83 | KMT2A (0.47) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL6760871 | 0.82 | HRH4 (0.48) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL6759291 | 0.81 | HRH4 (0.49) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL6757428 | 0.80 | HRH4 (0.46) | ALDH1A1KDM4ELMNANPC1HRH4 | |
| SCHEMBL6758072 | 0.79 | NPC1 (0.48) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL6757317 | 0.77 | SYK (0.44) | ALDH1A1KDM4ESMN1; SMN2HRH4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040204417-A1 | Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins | PIERRE FABRE MEDICAMENT (FR) | 2004-10-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204417-A1 | Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins | CBR1, CBR3, HCCS | ALDH1A1 2558/4885KDM4E 2166/4885LMNA 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.