Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759310 | 0.94 | ALDH1A1 (0.44) | HRH4ALDH1A1KMT2ALMNAPDE10A | |
| SCHEMBL6757317 | 0.91 | SYK (0.44) | HRH4ALDH1A1SYKKMT2ASMO | |
| SCHEMBL6758117 | 0.88 | HRH4 (0.48) | HRH4ALDH1A1SYKKMT2ALMNA | |
| SCHEMBL6757428 | 0.86 | HRH4 (0.46) | HRH4ALDH1A1SYKKMT2ALMNA | |
| SCHEMBL6757422 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SYKKMT2ALMNAPDE10A | |
| SCHEMBL6759291 | 0.84 | HRH4 (0.49) | HRH4ALDH1A1SYKKMT2ALMNA | |
| SCHEMBL6756425 | 0.84 | HRH4 (0.47) | HRH4ALDH1A1SYKKMT2ALMNA | |
| SCHEMBL6755014 | 0.82 | ALDH1A1 (0.44) | HRH4ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL6758252 | 0.79 | ALDH1A1 (0.45) | HRH4ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL6755065 | 0.78 | KMT2A (0.47) | HRH4ALDH1A1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040204417-A1 | Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins | PIERRE FABRE MEDICAMENT (FR) | 2004-10-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204417-A1 | Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins | CBR1, CBR3, HCCS | HRH4 42/4885ALDH1A1 2558/4885SYK 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.