Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690431 | 0.83 | HSPD1 (0.37) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL8746528 | 0.81 | HSPD1 (0.46) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL820028 | 0.81 | HSPD1 (0.46) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL375645 | 0.81 | HSPD1 (0.46) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL6663512 | 0.78 | HSPD1 (0.37) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL285119 | 0.78 | HSPD1 (0.43) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL8747679 | 0.78 | CES2 (0.38) | MEN1KMT2AHSD17B10PPARDGPR84 | |
| SCHEMBL9836187 | 0.77 | FOLH1 (0.31) | — | |
| SCHEMBL8747497 | 0.76 | CES2 (0.36) | MEN1KMT2AHSD17B10PPARDGPR84 | |
| SCHEMBL17995738 | 0.75 | HSPD1 (0.40) | HSPD1BLMHSPE1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9107804-B2 | Method of preparing biologically active formulations | NORTEC DEVELOPMENT ASSOCIATES, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-20040185111-A1 | pellet for use as a core for a dosage form, having an inner zone that includes the drug and an outer zone which includes a layer formed by applying a substantially dry, free flowing inert powder which forms a non-tacky surface in water; made with use of a rotating device | NORTEC DEVELOPMENT ASSOCIATES, INC. | 2004-09-23 | — | — | US | disclosed |