SCHEMBL675585

SCHEMBL675585

CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)N

nearest known ligand 0.85

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.85
TLR8 Q9NR97 13/20 0.85
NUDT1 P36639 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20199817 0.92 TLR7 (1.00) TLR7TLR8NUDT1
SCHEMBL24880278 0.90 TLR7 (0.88) TLR7TLR8NUDT1
Resiquimod SCHEMBL21352711 0.90 TLR7 (1.00) TLR7TLR8NUDT1
Resiquimod SCHEMBL29358122 0.90 TLR7 (1.00) TLR7TLR8NUDT1
Resiquimod SCHEMBL34159 0.90 TLR7 (1.00) TLR7TLR8NUDT1
Resiquimod SCHEMBL2262583 0.89 TLR7 (0.98) TLR7TLR8NUDT1
Resiquimod SCHEMBL2266073 0.89 TLR7 (0.98) TLR7TLR8NUDT1
SCHEMBL12330242 0.89 TLR7 (0.82) TLR7TLR8NUDT1
SCHEMBL3865523 0.89 TLR7 (0.68) TLR7TLR8NUDT1
SCHEMBL2743927 0.89 TLR7 (0.67) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY BIRDIE BIOPHARMACEUTICALS INC (KY) 2023-12-07 US claimed
US-11702476-B2 Anti-EGFR combinations for treating tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2023-07-18 US claimed
WO-2023097237-A2 CYTOSOLIC BACTERIAL PATHOGENS ATTENUATED FOR SPREAD FROM TUMORS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-06-01 WO claimed
US-11633495-B2 Compounds and compositions for immunotherapy BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2023-04-25 US claimed
US-11633494-B2 Compounds and compositions for immunotherapy BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2023-04-25 US claimed
EP-4148069-A1 ANTI-PD-L1 CONJUGATES FOR TREATING TUMORS Birdie Biopharmaceuticals Inc. (KY) 2023-03-15 EP claimed
CN-115554406-A anti-CD 20 combinations for the treatment of tumors 博笛生物科技有限公司 2023-01-03 CN claimed
CN-115350279-A anti-HER 2 combinations for the treatment of tumors 博笛生物科技有限公司 2022-11-18 CN claimed
CN-115337402-A Combination therapeutic compositions and combination therapeutic methods for treating cancer 博笛生物科技有限公司 2022-11-15 CN claimed
CN-115252792-A anti-EGFR combinations for the treatment of tumors 博笛生物科技有限公司 2022-11-01 CN claimed
US-20190002583-A1 ANTI-HER2 COMBINATIONS FOR TREATING TUMORS BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2019-01-03 US claimed
US-20180110874-A1 Compounds and Compositions for Immunotherapy SHANGHAI BIRDIE BIOTECH, INC. (CN) 2018-04-26 US claimed
US-9827329-B2 Compounds and compositions for immunotherapy BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2017-11-28 US claimed
US-20170290923-A1 Anti PD-L1 Conjugates for Treating Tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2017-10-12 US claimed
US-20170114137-A1 ANTI-PD-L1 COMBINATIONS FOR TREATING TUMORS SHANGHAI BIRDIE BIOTECH, INC. (CN) 2017-04-27 US claimed
US-20170056391-A1 COMBINATION THERAPY COMPOSITIONS AND METHODS FOR TREATING CANCERS BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2017-03-02 US claimed
US-20170028079-A1 Compounds and Compositions for Treating HER2 Positive Tumors SHANGHAI BIRDIE BIOTECH, INC. (CN) 2017-02-02 US claimed
US-20160375148-A1 Compounds and Compositions for Treating EGFR Expressing Tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2016-12-29 US claimed
US-20160324983-A1 Compounds and Compositions for Immunotherapy SHANGHAI BIRDIE BIOTECH, INC. (CN) 2016-11-10 US claimed
US-6888000-B2 Sulfonamide and sulfamide substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-05-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170114137-A1 ANTI-PD-L1 COMBINATIONS FOR TREATING TUMORS PDCD1LG2, CD274, PDCD1 TLR7 879/4885TLR8 585/4885NUDT1 3947/4885
US-20180110874-A1 Compounds and Compositions for Immunotherapy CD47, CD274, TP53 TLR7 147/4885TLR8 313/4885NUDT1 2607/4885
US-11633494-B2 Compounds and compositions for immunotherapy CD47, CD274, TP53 TLR7 147/4885TLR8 313/4885NUDT1 2607/4885
US-20170056391-A1 COMBINATION THERAPY COMPOSITIONS AND METHODS FOR TREATING CANCERS TP53, MCL1, MSH2 TLR7 1537/4885TLR8 2076/4885NUDT1 1375/4885
US-20190002583-A1 ANTI-HER2 COMBINATIONS FOR TREATING TUMORS ERBB2, FCGR2A, FCER2 TLR7 309/4885TLR8 427/4885NUDT1 3974/4885
US-20170028079-A1 Compounds and Compositions for Treating HER2 Positive Tumors ERBB2, EGFR, TP53 TLR7 362/4885TLR8 249/4885NUDT1 4309/4885
US-11702476-B2 Anti-EGFR combinations for treating tumors EGFR, ERBB3, ERBB2 TLR7 2007/4885TLR8 1153/4885NUDT1 3504/4885
US-11633495-B2 Compounds and compositions for immunotherapy CD47, CD274, TP53 TLR7 147/4885TLR8 313/4885NUDT1 2607/4885
US-20160324983-A1 Compounds and Compositions for Immunotherapy CD47, TP53, CD74 TLR7 198/4885TLR8 159/4885NUDT1 3366/4885
US-20160375148-A1 Compounds and Compositions for Treating EGFR Expressing Tumors EGFR, ERBB2, ERBB3 TLR7 634/4885TLR8 518/4885NUDT1 4361/4885
US-20170290923-A1 Anti PD-L1 Conjugates for Treating Tumors CD274, PDCD1LG2, PDCD1 TLR7 980/4885TLR8 901/4885NUDT1 4518/4885
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY CD47, CD274, TP53 TLR7 147/4885TLR8 313/4885NUDT1 2607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.