SCHEMBL675629

SCHEMBL675629

CC(Br)c1ccc(N)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
MAPT P10636 3/20 0.44
KMT2A Q03164 3/20 0.44
ALDH1A1 P00352 10/20 0.41
MAPK1 P28482 4/20 0.41
ALOX15 P16050 3/20 0.41
ACHE P22303 1/20 0.41
TDP1 Q9NUW8 7/20 0.38
CYP3A4 P08684 7/20 0.38
TP53 P04637 3/20 0.38
HIF1A Q16665 2/20 0.38
HTT P42858 2/20 0.38
GAA P10253 1/20 0.38
ALOX12 P18054 1/20 0.38
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
POLB P06746 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GRIA4 P48058 1/20 0.35
HSD17B10 Q99714 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL491250 0.97 MEN1 (0.42) MEN1MAPTKMT2AALDH1A1MAPK1
SCHEMBL1415320 0.85 ESR1 (0.38) MAPTALOX15TDP1CYP3A4HTT
SCHEMBL5695686 0.82 TYR (0.46) ALDH1A1MAPK1TP53HIF1AHTT
SCHEMBL5955 0.79 MAPT (0.53) MEN1MAPTKMT2AALDH1A1MAPK1
SCHEMBL3482829 0.77 ESR1 (0.52) MEN1MAPTKMT2AALDH1A1MAPK1
SCHEMBL9510147 0.77 PTGS2 (0.39) CYP3A4TP53NPC1RAB9A
Water SCHEMBL4672027 0.77 MAPT (0.50) MEN1MAPTKMT2AALDH1A1MAPK1
Ammonia Solution, Strong SCHEMBL28370828 0.77 MAPT (0.50) MEN1MAPTKMT2AALDH1A1MAPK1
SCHEMBL8164161 0.77 ESR1 (0.52) MEN1MAPTKMT2AALDH1A1MAPK1
SCHEMBL7518483 0.77 MEN1 (0.50) MEN1MAPTKMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10751896-B2 Shaving article with surface modification THE GILLETTE COMPANY LLC (US) 2020-08-25 US disclosed
US-9758506-B2 Muscarinic agonists HEPTARES THERAPEUTICS LIMITED (GB) 2017-09-12 US disclosed
US-9758506-B2 Muscarinic agonists HEPTARES THERAPEUTICS LIMITED (GB) 2017-09-12 US disclosed
US-20170037025-A1 Muscarinic Agonists NXERA PHARMA UK LIMITED (GB) 2017-02-09 US disclosed
US-20170037025-A1 Muscarinic Agonists NXERA PHARMA UK LIMITED (GB) 2017-02-09 US disclosed
EP-2326645-B9 COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT ACRAF (IT) 2013-04-17 EP disclosed
CN-101233117-B Multidentate aza ligands capable of complexing metal ions and their use in diagnostics and therapeutics BRACCO IMAGING SPA 2013-03-27 CN disclosed
US-8361908-B2 Modified surface material, method for preparing same and uses thereof UNIVERSITE PARIS 7-DENIS DIDEROT (FR) 2013-01-29 US disclosed
US-8361908-B2 Modified surface material, method for preparing same and uses thereof UNIVERSITE PARIS 7-DENIS DIDEROT (FR) 2013-01-29 US disclosed
EP-2326645-B1 COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT ACRAF (IT) 2012-11-07 EP disclosed
US-20060167199-A1 Process for produciton of living radical polymers and polymers OTSUKA CHEMICAL CO., LTD. (JP) 2006-07-27 US disclosed
US-20060135711-A1 Process for the production of living radical polymers and polymers OTSUKA CHEMICAL CO., LTD. (JP) 2006-06-22 US disclosed
CN-1780860-A Method for producing living radical polymer and polymer OTSUKA CHEMICAL CO LTD (JP) 2006-05-31 CN disclosed
EP-1619211-A1 PROCESS FOR PRODUCTION OF LIVING-RADICAL POLYMERS AND POLYMERS OTSUKA CHEMICAL COMPANY, LIMITED (JP) 2006-01-25 EP disclosed
EP-1595894-A1 PROCESS FOR THE PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS OTSUKA CHEMICAL COMPANY, LIMITED (JP) 2005-11-16 EP disclosed
US-20050245714-A1 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2005-11-03 US disclosed
CN-1675253-A Method for producing living radical polymer and polymer OTSUKA CHEMICAL CO LTD (JP) 2005-09-28 CN disclosed
CN-1649838-A Organic tellurium compound, method for producing same, living radical polymerization initiator, method for producing polymer using same, and polymer OTSUKA KAGAKU KK (JP) 2005-08-03 CN disclosed
EP-1541550-A1 ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER Otsuka Chemical Co., Ltd. (JP) 2005-06-15 EP disclosed
EP-1541592-A1 PROCESS FOR PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS OTSUKA CHEMICAL COMPANY, LIMITED (JP) 2005-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245714-A1 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer ODC1, TERB1, TTI1 MEN1 806/4885MAPT 1588/4885KMT2A 769/4885
US-20060135711-A1 Process for the production of living radical polymers and polymers CBR3, CBR1, CCNT1 MEN1 1560/4885MAPT 2999/4885KMT2A 1033/4885
US-20170037025-A1 Muscarinic Agonists CHRM1, CHRM2, CHRM3 MEN1 592/4885MAPT 2144/4885KMT2A 1818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.