Ethylene Glycol

Ethylene Glycol

SCHEMBL6756972

C(OCC1CO1)C1CO1.C=CCOCC=C.OCCO

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.74
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL1643309 0.94 ALDH1A1 (0.84) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL28295080 0.92 ALDH1A1 (0.87) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Ethylene Glycol SCHEMBL27324708 0.89 ALDH1A1 (0.75) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL27672259 0.88 ALDH1A1 (0.95) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Butadiene SCHEMBL3302346 0.86 ALDH1A1 (0.57) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL15162 0.86
SCHEMBL8064669 0.86
Di(Hydroxyethyl)Ether SCHEMBL5312498 0.85 ALDH1A1 (0.75) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Alcohol SCHEMBL6534676 0.85 ALDH1A1 (0.81) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Glycidol SCHEMBL27672258 0.85 ALDH1A1 (0.81) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118185330-A Epoxy asphalt material and preparation method and application thereof 黄卫 2024-06-14 CN disclosed
US-6787191-B2 Coating composition for the production of insulating thin films ASAHI KASEI KABUSHIKI KAISHA (JP) 2004-09-07 US disclosed
US-20040077757-A1 Coating composition for use in producing an insulating thin film ASAHI KASEI KABUSHIKI KAISHA (JP) 2004-04-22 US disclosed
US-20030099844-A1 Coating composition for the production of insulating thin films ASAHI KASEI KABUSHIKI KAISHA (JP) 2003-05-29 US disclosed