SCHEMBL675754

SCHEMBL675754

CNc1ccc(Cc2ccc(NC(=O)c3ccccc3C(=O)O)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
CYP1A2 P05177 1/20 0.56
GFER P55789 2/20 0.56
KMT2A Q03164 2/20 0.54
FFAR1 O14842 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.53
MAPT P10636 1/20 0.53
MEN1 O00255 1/20 0.52
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
ALOX12 P18054 1/20 0.51
APEX1 P27695 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16426269 0.92 ALDH1A1 (0.71) ALDH1A1CYP1A2GFERKMT2AFFAR1
SCHEMBL19799370 0.92 ALDH1A1 (0.76) ALDH1A1CYP1A2GFERKMT2ASMN1; SMN2
SCHEMBL25918279 0.90 ALDH1A1 (0.65) ALDH1A1CYP1A2GFERKMT2AFFAR1
SCHEMBL1695994 0.90 ALDH1A1 (0.63) ALDH1A1CYP1A2GFERKMT2AFFAR1
SCHEMBL23409198 0.87 ALDH1A1 (0.63) ALDH1A1CYP1A2GFERKMT2AFFAR1
SCHEMBL18132553 0.85 ALDH1A1 (0.65) ALDH1A1CYP1A2GFERKMT2AFFAR1
SCHEMBL7829395 0.84 ALDH1A1 (0.70) ALDH1A1CYP1A2GFERKMT2AFFAR1
SCHEMBL675767 0.84 MEN1 (0.71) ALDH1A1CYP1A2GFERKMT2ASMN1; SMN2
SCHEMBL13927135 0.83 ALDH1A1 (0.92) ALDH1A1CYP1A2GFERKMT2AMEN1
SCHEMBL12615048 0.83 ALDH1A1 (0.71) ALDH1A1CYP1A2GFERKMT2AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718751-B2 Water-borne polymer composition SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2023-08-08 US disclosed
US-11685829-B2 Process for preparing particles of aromatic polymers, particles obtainable by said process and their uses SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-06-27 US disclosed
US-10947345-B2 Varnish for photo alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2021-03-16 US disclosed
US-20180022874-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2018-01-25 US disclosed
US-20180022874-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2018-01-25 US disclosed
US-20170292022-A1 Sulfone polymer composition SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-10-12 US disclosed
US-20170292022-A1 Sulfone polymer composition SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-10-12 US disclosed
US-20170145242-A1 FLUOROPOLYMER COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2017-05-25 US disclosed
US-20170145242-A1 FLUOROPOLYMER COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2017-05-25 US disclosed
US-20170121594-A1 Proppant particulates and methods of using such particulates in subterranean applications SOLVAY SPECIALTY POLYMERS USA (US) 2017-05-04 US disclosed
US-20110263729-A1 Fiber or Foil from Polymers with High Tg and Process for their Manufacture SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-10-27 US disclosed
US-8008408-B2 Aromatic polyimide composition and articles manufactured therefrom Solvay (Société Anonyme) (BE) 2011-08-30 US disclosed
US-7985790-B2 Water-based fluoropolymer composition SOLVAY SOLEXIS, S.P.A. (IT) 2011-07-26 US disclosed
US-7820767-B2 Aromatic polyimide composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-10-26 US disclosed
US-20090162676-A1 Overmolded Plastic Articles, Uses Thereof, Method Of Making SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-06-25 US disclosed
US-20090069507-A1 Aromatic Polyimide Composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-03-12 US disclosed
US-20090018244-A1 Water-Based Fluoropolymer Composition SOLVAY SOLEXIS, S.P.A. (IT) 2009-01-15 US disclosed
US-20080275162-A1 Ptfe-Based Compositions SOLVAY (SOCIETE ANONYME) (BE) 2008-11-06 US disclosed
US-20080014423-A1 Fluoropolymer Tape, Article Comprising a Fluoropolymer Tape and Process for Manufacturing a Fluoropolymer Tape SOLVAY (SOCIETE ANONYMW (BE) 2008-01-17 US disclosed
US-20070222108-A1 Aromatic Polyimide Composition and Articles Manufactured Therefrom SOLVAY (SOCIETE ANONYME) (BE) 2007-09-27 US disclosed