Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16426269 | 0.91 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP1A2 | |
| SCHEMBL10489953 | 0.91 | ALDH1A1 (0.76) | ALDH1A1TDP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL675754 | 0.90 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL25918279 | 0.88 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL23409198 | 0.85 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP1A2 | |
| SCHEMBL12643348 | 0.84 | TDP1 (0.55) | ALDH1A1TDP1SMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL7058035 | 0.84 | RAB9A (0.79) | ALDH1A1TDP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18132553 | 0.84 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL7829395 | 0.83 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL27351659 | 0.83 | PLG (0.48) | ALDH1A1TDP1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822558-B2 | Low density hydrophobic material and method of making the same | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-09-02 | — | — | US | disclosed |
| US-20120088855-A1 | LOW DENSITY HYDROPHOBIC MATERIAL AND METHOD OF MAKING THE SAME | CASE WESTERN RESERVE UNIVERSITY (US) | 2012-04-12 | — | — | US | disclosed |