SCHEMBL6757883

SCHEMBL6757883

BrCCCCCCSc1nc2ccccc2[nH]1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.71
NPC1 O15118 4/20 0.68
RAB9A P51151 4/20 0.68
AR P10275 3/20 0.65
ALDH1A1 P00352 2/20 0.63
EPHX2 P34913 1/20 0.63
LMNA P02545 4/20 0.62
SMN1; SMN2 Q16637 5/20 0.58
POLB P06746 1/20 0.58
KMT2A Q03164 4/20 0.56
MAPT P10636 2/20 0.56
HTT P42858 1/20 0.56
TP53 P04637 2/20 0.56
MEN1 O00255 2/20 0.54
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
MAPK1 P28482 1/20 0.51
HSD17B10 Q99714 1/20 0.51
HPGD P15428 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14304381 0.92 BCHE (0.83) BCHENPC1RAB9AARALDH1A1
SCHEMBL14304387 0.92 BCHE (0.83) BCHENPC1RAB9AARALDH1A1
SCHEMBL14303260 0.92 BCHE (0.83) BCHENPC1RAB9AARALDH1A1
SCHEMBL6141660 0.92 BCHE (0.83) BCHENPC1RAB9AARALDH1A1
SCHEMBL14303261 0.92 BCHE (0.83) BCHENPC1RAB9AARALDH1A1
Bromide SCHEMBL5084026 0.91 BCHE (0.80) BCHENPC1RAB9AARALDH1A1
SCHEMBL14304932 0.91 BCHE (0.86) BCHENPC1RAB9AARALDH1A1
SCHEMBL6608285 0.86 EPHX2 (0.79) BCHENPC1RAB9AARALDH1A1
SCHEMBL6605155 0.86 EPHX2 (0.79) BCHENPC1RAB9AARALDH1A1
SCHEMBL6604271 0.86 EPHX2 (0.79) BCHENPC1RAB9AARALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6787561-B1 HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES FUJI PHOTO FILM CO., LTD. (JP) 2004-09-07 US disclosed
EP-1412404-A1 COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE Cohesion Technologies, Inc. (US) 2004-04-28 EP disclosed
WO-2002102864-A1 COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE COHESION TECHNOLOGIES, INC. (US) 2002-12-27 WO disclosed
EP-1197493-A1 BENZIMIDAZOLE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 2002-04-17 EP disclosed