Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759297 | 0.93 | HRH4 (0.47) | KDM4ELMNANPC1RAB9AHRH3 | |
| SCHEMBL6758074 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL6759304 | 0.81 | HRH4 (0.52) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL6758255 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL6759314 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL6755015 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL6755081 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL6755068 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL6619162 | 0.75 | RXFP1 (0.44) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL6755079 | 0.75 | LMNA (0.41) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040204417-A1 | Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins | PIERRE FABRE MEDICAMENT (FR) | 2004-10-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204417-A1 | Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins | CBR1, CBR3, HCCS | ALDH1A1 2558/4885KDM4E 2166/4885SMN1; SMN2 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.