SCHEMBL6758779

SCHEMBL6758779

CCn1cnc2cc(C(F)(F)F)ccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.51
NPC1 O15118 8/20 0.49
RAB9A P51151 7/20 0.49
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
GAA P10253 1/20 0.49
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 4/20 0.48
MAPT P10636 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
QPCT Q16769 1/20 0.45
QPCTL Q9NXS2 1/20 0.45
PKM P14618 1/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19848394 0.89 NPSR1 (0.48) NPSR1NPC1RAB9AGAAKDM4E
SCHEMBL11347338 0.87 PRPS1 (0.48) NPSR1NPC1RAB9AKMT2AMEN1
SCHEMBL12873184 0.87 NPC1 (0.49) NPC1RAB9AKMT2AMEN1GAA
SCHEMBL19848378 0.86 LMNA (0.56) NPSR1NPC1RAB9AGAAKDM4E
SCHEMBL21992429 0.84 NPSR1 (0.44) NPSR1NPC1RAB9AKMT2AMEN1
SCHEMBL31202825 0.83 QPCT (0.43) NPSR1KMT2AMEN1ALDH1A1MAPT
SCHEMBL9570127 0.83 NPSR1 (0.45) NPSR1GAAMAPTSMN1; SMN2HSD17B10
SCHEMBL9598373 0.83 NPSR1 (0.48) NPSR1NPC1RAB9AGAAKDM4E
SCHEMBL6176862 0.82 NPSR1 (0.46) NPSR1NPC1RAB9AGAAMAPT
SCHEMBL30914205 0.82 MEN1 (0.57) NPSR1NPC1RAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-12421218-B2 Substituted pyrazine-carboxamide derivatives BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-09-23 US disclosed
US-20240417394-A1 NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES BOEHRINGER INGELHEIM INT (DE) 2024-12-19 US disclosed
US-20240182453-A1 NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2024-06-06 US disclosed
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-08-25 US disclosed
EP-3467930-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-04-10 EP disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
EP-3279997-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY Asahi Kasei Kabushiki Kaisha (JP) 2018-02-07 EP disclosed
US-6828088-B2 Contrast and sensitivity FUJI PHOTO FILM CO., LTD. (JP) 2004-12-07 US disclosed
US-4046572-A SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JA) 1977-09-06 US disclosed
US-4040841-A SENSITIZING DYE FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4030927-A PHOTOGRAPHIC SILVER HALIDE EMULSIONS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-21 US disclosed
US-4018610-A Supersensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1977-04-19 US disclosed
US-4002480-A CONTAINING A DINUCLEAR MEROCYANINE SENSITIZING DYE AND AN ANTIFOGGING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1977-01-11 US disclosed
US-3994733-A CYANINE DYES, A BENZOTHIAZOLE, OR BENZOTHIAZOLONE, OR NAPHTHOTHIAZOLE, OR NAPHTHOTHIAZOLONE, OR A QUINOLONE FUJI PHOTO FILM CO., LTD. (JA) 1976-11-30 US disclosed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US disclosed
US-3951666-A CYANINE AND MEROCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421218-B2 Substituted pyrazine-carboxamide derivatives GRM4, GRIA4, GRM1 NPSR1 220/4885NPC1 1174/4885RAB9A 2587/4885
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery BPTF, BRD4, KCNN2 NPSR1 3412/4885NPC1 2529/4885RAB9A 3611/4885
US-20240417394-A1 NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES GRIA4, GRM4, GRM1 NPSR1 200/4885NPC1 1467/4885RAB9A 2453/4885
US-20240182453-A1 NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES GRIA4, GRM4, GRM1 NPSR1 200/4885NPC1 1467/4885RAB9A 2453/4885
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery BPTF, BRD4, KCNN2 NPSR1 3412/4885NPC1 2529/4885RAB9A 3611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.