Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029147 | 0.88 | CA12 (0.38) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL5026616 | 0.86 | CA14 (0.40) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL25699642 | 0.83 | SSTR4 (0.40) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL5721018 | 0.83 | HDAC6 (0.38) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL19491344 | 0.80 | CA14 (0.38) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL2608081 | 0.78 | CA14 (0.49) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL7905771 | 0.77 | CA14 (0.44) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL9901110 | 0.77 | CA14 (0.44) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL1352475 | 0.75 | HDAC6 (0.36) | CA14HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL20077109 | 0.75 | CA14 (0.43) | CA14CA12CA1CA7HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624250-A | Platinum (IV) prodrug with novel NF- κB inhibitor as ligand and preparation method and application thereof | 淮阴工学院 | 2024-03-01 | — | — | CN | claimed |
| WO-2024199098-A1 | XANTHINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 麦科奥特(苏州)科技有限公司 | 2024-10-03 | — | — | WO | disclosed |
| WO-2024199096-A1 | ANTICOAGULATION REVERSAL AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 陕西麦科奥特科技有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-118684671-A | Xanthine derivative and preparation method and application thereof | 麦科奥特(苏州)科技有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-118684672-A | Anticoagulation reversal agent and preparation method and application thereof | 陕西麦科奥特科技有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-117624250-A | Platinum (IV) prodrug with novel NF- κB inhibitor as ligand and preparation method and application thereof | 淮阴工学院 | 2024-03-01 | — | — | CN | disclosed |
| EP-3884939-B1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS INC (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-115746034-A | Three-function organic catalyst, preparation method and application thereof | 浙江大学 | 2023-03-07 | — | — | CN | disclosed |
| EP-3884939-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | Raze Therapeutics, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| WO-2020033322-A1 | HEARING LOSS-PROTECTIVE COMPOUNDS AND METHODS THEREOF | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2020-02-13 | — | — | WO | disclosed |
| EP-1293214-A2 | LTB4 antagonists and radiopharmaceuticals for imaging infection and inflammation | Bristol-Myers Squibb Pharma Company (US) | 2003-03-19 | — | — | EP | disclosed |
| US-20030007927-A1 | Radiopharmaceuticals for imaging infection and inflammation | BARRETT JOHN A (US) | 2003-01-09 | — | — | US | disclosed |
| US-20030003049-A1 | Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation | LANTHEUS MEDICAL IMAGING, INC. | 2003-01-02 | — | — | US | disclosed |
| EP-1250324-A1 | BIARYL COMPOUNDS, THEIR PREPARATION AND THEIR USE IN THERAPY | RiboTargets Limited (GB) | 2002-10-23 | — | — | EP | disclosed |
| US-6416733-B1 | RADIOPHARMACEUTICALS BIND IN VIVO TO THE LEUKOTRIENE B4 (LTB4) RECEPTOR ON THE SURFACE OF LEUKOCYTES WHICH ACCUMULATE AT THE SITE OF INFECTION AND INFLAMMATION | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-07-09 | — | — | US | disclosed |
| WO-2002036173-A2 | SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-05-10 | — | — | WO | disclosed |
| WO-2001055111-A1 | BIARYL COMPOUNDS, THEIR PREPARATION AND THEIR USE IN THERAPY | RIBOTARGETS LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |
| EP-0999856-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | Du Pont Pharmaceuticals Company (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1998015295-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | DUPONT PHARMACEUTICALS COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| WO-1997046525-A1 | 5-ALKOXY-TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS 5-HT1D RECEPTOR AGONISTS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030007927-A1 | Radiopharmaceuticals for imaging infection and inflammation | LTB4R, LTB4R2, LTA4H | CA14 3683/4885CA12 3946/4885CA1 4752/4885 |
| US-20030003049-A1 | Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation | LTB4R, LTB4R2, FABP3 | CA14 2484/4885CA12 2670/4885CA1 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.