SCHEMBL6759897

SCHEMBL6759897

CCOC(=O)CCC=CCCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.50
CYP4A11 Q02928 2/20 0.50
GPR52 Q9Y2T5 1/20 0.49
FFAR1 O14842 1/20 0.47
ALOX5 P09917 1/20 0.46
MGLL Q99685 3/20 0.45
PTPN1 P18031 1/20 0.45
FAAH O00519 1/20 0.45
CYP4Z1 Q86W10 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6759891 1.00 CYP4F2 (0.50) CYP4F2CYP4A11GPR52FFAR1ALOX5
SCHEMBL6756479 0.91 ALOX5 (0.53) CYP4F2CYP4A11GPR52ALOX5TDP1
SCHEMBL6756477 0.91 ALOX5 (0.53) CYP4F2CYP4A11GPR52ALOX5TDP1
SCHEMBL9672285 0.90 CYP4F2 (0.60) CYP4F2CYP4A11ALOX5CYP4Z1TDP1
SCHEMBL9672286 0.90 CYP4F2 (0.60) CYP4F2CYP4A11ALOX5CYP4Z1TDP1
SCHEMBL2772418 0.85 CYP4F2 (0.68) CYP4F2CYP4A11FFAR1ALOX5MGLL
SCHEMBL9671724 0.83 ALOX5 (0.58) CYP4F2CYP4A11ALOX5CYP4Z1TDP1
SCHEMBL9671726 0.83 ALOX5 (0.58) CYP4F2CYP4A11ALOX5CYP4Z1TDP1
SCHEMBL1912585 0.82 ALOX5 (0.64) CYP4F2CYP4A11FFAR1ALOX5MGLL
SCHEMBL6759988 0.82 GLA (0.52) CYP4F2CYP4A11GPR52ALOX5CYP4Z1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040034097-A1 Pesticidal activity of functionalized alkenes LINDERMAN RUSSELL J (US) 2004-02-19 US claimed
US-20020193436-A1 Pesticidal activity of functionalized alkenes NORTH CAROLINA STATE UNIVERSITY 2002-12-19 US claimed
WO-2002098220-A2 PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES NORTH CAROLINA STATE UNIVERSITY (US) 2002-12-12 WO claimed
US-6720450-B2 USING SUCH AS 7-CYCLOHEXYL-(4,5-METHANO)HEPTANOIC ACID; CONTROLLING BLOOD INGESTING INSECTS NORTH CAROLINA STATE UNIVERSITY 2004-04-13 US disclosed
US-20040034097-A1 Pesticidal activity of functionalized alkenes LINDERMAN RUSSELL J (US) 2004-02-19 US disclosed
US-6660770-B2 Inhibit digestion by terminating or blocking synthesis of digestive enzymes by activating trypsin modulating oostatic factor receptor NORTH CAROLINA STATE UNIVERSITY 2003-12-09 US disclosed
US-20030149103-A1 Pesticidal activity of functionalized cyclopropanes NORTH CAROLINA STATE UNIVERSITY 2003-08-07 US disclosed
WO-2003051118-A1 PESTICIDAL ACTIVITY OF FUNCTIONALIZED CYCLOPROPANES NORTH CAROLINA STATE UNIVERSITY (US) 2003-06-26 WO disclosed
US-20020193436-A1 Pesticidal activity of functionalized alkenes NORTH CAROLINA STATE UNIVERSITY 2002-12-19 US disclosed
WO-2002098220-A2 PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES NORTH CAROLINA STATE UNIVERSITY (US) 2002-12-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193436-A1 Pesticidal activity of functionalized alkenes VIP, ANPEP, APEH CYP4F2 133/4885CYP4A11 808/4885GPR52 780/4885
US-20040034097-A1 Pesticidal activity of functionalized alkenes VIP, ANPEP, APEH CYP4F2 133/4885CYP4A11 808/4885GPR52 780/4885
US-20030149103-A1 Pesticidal activity of functionalized cyclopropanes DDT, PPIF, CYP4F3 CYP4F2 10/4885CYP4A11 266/4885GPR52 2429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.