Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760237 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL6764215 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL6764213 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL13455873 | 0.82 | GLO1 (0.39) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL13424250 | 0.82 | GLO1 (0.39) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL3430617 | 0.81 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| Ammonia Solution, Strong SCHEMBL27426631 | 0.79 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| SCHEMBL27314897 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL4917886 | 0.77 | NPSR1 (0.36) | ALDH1A1LMNAHSD17B10GLO1MAPT | |
| SCHEMBL11141816 | 0.77 | ALDH1A1 (0.58) | ALDH1A1LMNAHSD17B10GLO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723313-B2 | FRAGRANCE, AN AROMA, OR A FLAVORING AGENT FOR PERFUMES, DETERGENTS, SOAPS, CREAMS, SHAMPOOS, HAIR CONDITIONERS, FOODS | GIVAUDAN SA (CH) | 2004-04-20 | — | — | US | disclosed |
| EP-1149820-B1 | 2-,5-,6-,7-,8-substituted oct-2-ene-4-one | GIVAUDAN SA (CH) | 2003-07-30 | — | — | EP | disclosed |
| US-20020176838-A1 | 2-,5-,6-,7-,8-substituted oct-2-en-4-ones | GIVAUDAN SA | 2002-11-28 | — | — | US | disclosed |
| EP-1149820-A1 | 2-,5-,6-,7-,8-substituted oct-2-ene-4-one | Givaudan SA (CH) | 2001-10-31 | — | — | EP | disclosed |