Acetic Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA2A ADRA2B ADRA2C ADRB2 AGTR1 AVPR1A AVPR1B AVPR2 BDKRB2 CALCR CHRNA3 CHRNB4 ESR1 ESR2 GHSR GNRHR GSC1 HSPA8 MALT1 MC1R MC4R NOS1 NOS2 NOS3 OPRK1 OXTR RAMP1 RAMP2 RAMP3 SCN5A SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 dacA dacB dacC folP ftsI mrcA mrcB mrdA rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	1/20	0.57

▸	CYP4F2	P78329	3/20	0.47

▸	CYP4A11	Q02928	3/20	0.47

▸	GAA	P10253	2/20	0.46

▸	MGAM	O43451	1/20	0.46

▸	SI	P14410	1/20	0.46

▸	MGAM2	Q2M2H8	1/20	0.46

▸	NR1I2	O75469	1/20	0.46

▸	PGR	P06401	1/20	0.46

▸	ADORA3	P0DMS8	1/20	0.46

▸	PTGS2	P35354	1/20	0.46

▸	PDE4D	Q08499	1/20	0.46

▸	ALDH1A1	P00352	4/20	0.43

▸	HSD17B10	Q99714	2/20	0.43

▸	CYP3A4	P08684	1/20	0.43

▸	ALOX15	P16050	1/20	0.43

▸	TSHR	P16473	1/20	0.43

▸	TDP1	Q9NUW8	1/20	0.43

▸	TRPA1	O75762	1/20	0.43

▸	PAM	P19021	2/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Acetic Acid SCHEMBL4859810	1.00	CYP1A2 (0.57)	CYP1A2CYP4F2CYP4A11GAAMGAM
Acetic Acid SCHEMBL988009	1.00	CYP1A2 (0.57)	CYP1A2CYP4F2CYP4A11GAAMGAM
Acetic Acid SCHEMBL5961214	1.00	CYP1A2 (0.57)	CYP1A2CYP4F2CYP4A11GAAMGAM
Acetic Acid SCHEMBL988260	1.00	CYP1A2 (0.57)	CYP1A2CYP4F2CYP4A11GAAMGAM
Acetic Acid SCHEMBL989387	1.00	CYP1A2 (0.57)	CYP1A2CYP4F2CYP4A11GAAMGAM
Acetic Acid SCHEMBL15993372	1.00	CYP1A2 (0.57)	CYP1A2CYP4F2CYP4A11GAAMGAM
Acetic Acid SCHEMBL1149338	1.00	CYP1A2 (0.57)	CYP1A2CYP4F2CYP4A11GAAMGAM
Acetic Acid SCHEMBL5722467	1.00	CYP1A2 (0.57)	CYP1A2CYP4F2CYP4A11GAAMGAM
Acetic Acid SCHEMBL1816394	1.00	CYP1A2 (0.57)	CYP1A2CYP4F2CYP4A11GAAMGAM
Acetic Acid SCHEMBL991294	1.00	CYP1A2 (0.57)	CYP1A2CYP4F2CYP4A11GAAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20040138203-A1	Bicyclic lactams and sulfonamides with 5-ht1a -affinity and use thereof for preventing and treating cerebral ischaemia	STEINER GERD	2004-07-15	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20040138203-A1	Bicyclic lactams and sulfonamides with 5-ht1a -affinity and use thereof for preventing and treating cerebral ischaemia	HTR1A, HTR5A, HTR2C	CYP1A2 91/4885CYP4F2 1001/4885CYP4A11 869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.