Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760353 | 1.00 | GRIN1 (0.39) | GRIN1GRIN2BEPHX2MAPK1MEN1 | |
| SCHEMBL6760359 | 0.88 | MAPK1 (0.51) | GRIN1GRIN2BEPHX2MAPK1MEN1 | |
| SCHEMBL6760357 | 0.88 | MAPK1 (0.51) | GRIN1GRIN2BEPHX2MAPK1MEN1 | |
| SCHEMBL6758352 | 0.88 | TSHR (0.43) | GRIN1GRIN2BEPHX2MEN1KMT2A | |
| SCHEMBL6758359 | 0.88 | TSHR (0.43) | GRIN1GRIN2BEPHX2MEN1KMT2A | |
| SCHEMBL6758160 | 0.87 | OPRK1 (0.39) | EPHX2MAPK1MEN1KMT2ANAAA | |
| SCHEMBL6758164 | 0.87 | OPRK1 (0.39) | EPHX2MAPK1MEN1KMT2ANAAA | |
| SCHEMBL6762776 | 0.87 | MAPK1 (0.40) | GRIN1GRIN2BEPHX2MAPK1MEN1 | |
| SCHEMBL6761310 | 0.87 | CCR1 (0.42) | GRIN1GRIN2BEPHX2MAPK1MEN1 | |
| SCHEMBL6762783 | 0.87 | MAPK1 (0.40) | GRIN1GRIN2BEPHX2MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063688-A1 | Novel piperidine derivatives | PFIZER INC. | 2004-04-01 | — | — | US | claimed |
| US-20040063688-A1 | Novel piperidine derivatives | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063688-A1 | Novel piperidine derivatives | CCR1, CCR3, CCR2 | GRIN1 1153/4885GRIN2B 2149/4885EPHX2 3279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.